Document Detail


The prevalence of Entamoeba histolytica in lactating women and in their infants in Bangladesh.
MedLine Citation:
PMID:  2902705     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Entamoeba histolytica was studied in 33 lactating women and their infants in a periurban village in Bangladesh. Infant-mother pairs were followed for a period of 10-15 months: 67% of mothers excreted E. histolytica during the observation period, the majority for 3 months or more. Only one mother was symptomatic, with a mild, non-dysenteric diarrhoea. 58% of mothers were seropositive, several of them continuously and with a high titre, indicating past invasive infection. 67% had detectable antibodies in breast milk and 36% in saliva. Despite the high prevalence of E. histolytica in these mothers, infants were mostly uninfected: E. histolytica cysts in small numbers were found in only 2 of 1200 samples from infants aged 6 and 10 months. Several of the children were infected with Giardia lamblia. Although lower exposure to E. histolytica than to Giardia may account for the difference in infant infection rates with these parasites, defence mechanisms possibly exist which protect against E. histolytica but are ineffective against Giardia.
Authors:
A Islam; B J Stoll; I Ljungstrom; J Biswas; H Nazrul; G Huldt
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Transactions of the Royal Society of Tropical Medicine and Hygiene     Volume:  82     ISSN:  0035-9203     ISO Abbreviation:  Trans. R. Soc. Trop. Med. Hyg.     Publication Date:  1988  
Date Detail:
Created Date:  1988-11-23     Completed Date:  1988-11-23     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7506129     Medline TA:  Trans R Soc Trop Med Hyg     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  99-103     Citation Subset:  IM    
Affiliation:
International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Amebiasis / epidemiology*
Animals
Antibodies, Protozoan / analysis
Bangladesh
Entamoeba histolytica / immunology,  isolation & purification
Entamoebiasis / epidemiology*
Feces / parasitology
Female
Humans
Immunoglobulin A, Secretory / analysis
Immunoglobulin G / analysis
Infant
Lactation*
Milk, Human / immunology
Pregnancy
Saliva / immunology
Chemical
Reg. No./Substance:
0/Antibodies, Protozoan; 0/Immunoglobulin A, Secretory; 0/Immunoglobulin G

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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