Document Detail

A pressure-controlled rat ventilator with electronically preset respirations.
MedLine Citation:
PMID:  17181839     Owner:  NLM     Status:  MEDLINE    
Major experimental surgery on laboratory animals requires adequate anesthesia and ventilation to keep the animal alive throughout the procedure. A ventilator is a machine that helps the anesthesized animal breathe through an endotracheal tube by pumping a volume of gas (oxygen, air, or other gaseous mixtures), comparable with the normal tidal volume, into the animal's lungs. There are two main categories of ventilators for small laboratory rodents: volume-controlled and pressure-controlled ones. The volume-controlled ventilator injects a preset volume into the animal's lungs, no matter the airways' resistance (with the peak inspiratory pressure allowed to vary), while the pressure ventilator controls the inspiratory pressure and allows the inspiratory volume to vary. Here we show a rat pressure ventilator with a simple expiratory valve that allows gas delivery through electronic expiration control and offers easy pressure monitoring and frequency change during ventilation.
Valentin L Ordodi; V Paunescu; Ani A Mic; Lazar Gabor; Mihai Ionac; Octavian Toma; Dorel Sandesc; Felix A Mic
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Artificial organs     Volume:  30     ISSN:  0160-564X     ISO Abbreviation:  Artif Organs     Publication Date:  2006 Dec 
Date Detail:
Created Date:  2006-12-21     Completed Date:  2007-03-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7802778     Medline TA:  Artif Organs     Country:  United States    
Other Details:
Languages:  eng     Pagination:  965-8     Citation Subset:  IM    
Department of Physiology, University of Medicine and Pharmacy Victor Babes, Timisoara, Romania.
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MeSH Terms
Equipment Design
Monitoring, Physiologic / instrumentation*
Pulmonary Gas Exchange
Pulmonary Ventilation
Ventilators, Mechanical*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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