Document Detail

A pressure-controlled rat ventilator with electronically preset respirations.
MedLine Citation:
PMID:  17181839     Owner:  NLM     Status:  MEDLINE    
Major experimental surgery on laboratory animals requires adequate anesthesia and ventilation to keep the animal alive throughout the procedure. A ventilator is a machine that helps the anesthesized animal breathe through an endotracheal tube by pumping a volume of gas (oxygen, air, or other gaseous mixtures), comparable with the normal tidal volume, into the animal's lungs. There are two main categories of ventilators for small laboratory rodents: volume-controlled and pressure-controlled ones. The volume-controlled ventilator injects a preset volume into the animal's lungs, no matter the airways' resistance (with the peak inspiratory pressure allowed to vary), while the pressure ventilator controls the inspiratory pressure and allows the inspiratory volume to vary. Here we show a rat pressure ventilator with a simple expiratory valve that allows gas delivery through electronic expiration control and offers easy pressure monitoring and frequency change during ventilation.
Valentin L Ordodi; V Paunescu; Ani A Mic; Lazar Gabor; Mihai Ionac; Octavian Toma; Dorel Sandesc; Felix A Mic
Related Documents :
3526789 - Central haemodynamics and oxygen transport during cppv with frequencies of 16 and 8 tim...
2117169 - Gas exchange abnormalities in asthma.
339649 - High-frequency positive-pressure ventilation (hfppv) in neonates and infants during neu...
1931409 - Delayed pneumothorax after subclavian vein catheterization and positive pressure ventil...
8149509 - Pulmonary vascular effects of endotoxin in canine lobes pretreated with dapsone.
18097649 - Terbutaline lessens protein fluxes across the alveolo-capillary barrier during high-vol...
3964869 - Artificial sphincter pressure versus detrusor leakage pressure.
24158199 - Brain-type natriuretic peptide and right ventricular end-diastolic volume index measure...
8712329 - The effect of increasing the dose of buprenorphine on the haemodynamic response associa...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Artificial organs     Volume:  30     ISSN:  0160-564X     ISO Abbreviation:  Artif Organs     Publication Date:  2006 Dec 
Date Detail:
Created Date:  2006-12-21     Completed Date:  2007-03-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7802778     Medline TA:  Artif Organs     Country:  United States    
Other Details:
Languages:  eng     Pagination:  965-8     Citation Subset:  IM    
Department of Physiology, University of Medicine and Pharmacy Victor Babes, Timisoara, Romania.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Equipment Design
Monitoring, Physiologic / instrumentation*
Pulmonary Gas Exchange
Pulmonary Ventilation
Ventilators, Mechanical*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Late results of gelatin-resorcin-formalin glue-aided repair in acute type A aortic dissection.
Next Document:  Tumour-associated angiogenesis in human colorectal cancer.