| The presentation of 6-mercaptopurine overdose in ED. | |
| | |
MedLine Citation:
|
PMID: 19555631 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
6-Mercaptopurine (6-MP), although an effective immunosuppressive when used in the treatment of certain cancers, can have devastating effects when ingested accidentally or used in excessive amounts. We report here the case of an unintentional ingestion of a large amount of 6-MP by a woman with hypothyroidism who was erroneously given this antimetabolic agent by her pharmacist instead the propylthiouracil (PTU) she was actually prescribed. This is one of several documented cases in which 6-MP has been dispensed instead of PTU. Because of the myelosuppressive and hepatotoxic effects of 6-MP, this case reinforces the need for both physicians and patients to understand the importance of examining their medications before ingestion. |
| | |
Authors:
|
Neeraj Gupta; Christopher C Lee; Tae Ho Lim; Adam J Singer |
Publication Detail:
|
Type: Case Reports; Journal Article |
Journal Detail:
|
Title: The American journal of emergency medicine Volume: 27 ISSN: 1532-8171 ISO Abbreviation: Am J Emerg Med Publication Date: 2009 May |
Date Detail:
|
Created Date: 2009-06-26 Completed Date: 2009-07-21 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8309942 Medline TA: Am J Emerg Med Country: United States |
Other Details:
|
Languages: eng Pagination: 513.e1-2 Citation Subset: IM |
Affiliation:
|
Stony Brook University, School of Medicine, Stony Brook, NY, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
6-Mercaptopurine
/
poisoning* Adult Antimetabolites, Antineoplastic / poisoning* Antithyroid Agents Blepharoptosis / chemically induced Female Humans Hyperthyroidism / drug therapy Medication Errors / prevention & control Overdose / diagnosis, therapy Propylthiouracil |
| Chemical | |
Reg. No./Substance:
|
0/Antimetabolites, Antineoplastic; 0/Antithyroid Agents; 50-44-2/6-Mercaptopurine; 51-52-5/Propylthiouracil |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Intraventricular conduction abnormality--an electrocardiographic algorithm for rapid detection and d...
Next Document: Middle turbinectomy as a complication of nasopharyngeal airway placement.