Document Detail

The presence and specificity of crustacean cardioactive peptide (CCAP)-immunoreactivity in gastropod neurons.
MedLine Citation:
PMID:  11034139     Owner:  NLM     Status:  MEDLINE    
CCAP-like immunoreactivity was detected in central neurons with small and medium diameters in both Helix and Lymnaea CNS. The intensity of immunoreactivity showed seasonal changes with a maximum intensity during spring. The overwhelming majority of nerve cell bodies exhibiting CCAP immunoreactivity is located in the cerebral and parietal ganglia of both Helix and Lymnaea. The neurons of pleural and buccal ganglia were devoid of CCAP-immunoreactivity. Following preabsorbtion of CCAP antibody in 1:15000 dilution with 10(-3) M CCAP or CCAP-related peptide (Helix -CCAP), immunoreactivity could not be observed in neurons, demonstrating the specificity of the antibody to CCAP-related molecules in both Helix and Lymnaea.
L Hernádi; H J Agricola
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta biologica Hungarica     Volume:  51     ISSN:  0236-5383     ISO Abbreviation:  Acta. Biol. Hung.     Publication Date:  2000  
Date Detail:
Created Date:  2001-02-13     Completed Date:  2001-02-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8404358     Medline TA:  Acta Biol Hung     Country:  HUNGARY    
Other Details:
Languages:  eng     Pagination:  147-52     Citation Subset:  IM    
Department of Experimental Zoology, Balaton Limnological Research Institute of the Hungarian Academy of Sciences, Tihany.
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MeSH Terms
Amino Acid Sequence
Central Nervous System / metabolism
Helix (Snails) / metabolism*
Lymnaea / metabolism*
Neurons / metabolism
Neuropeptides / chemistry,  metabolism*
Reg. No./Substance:
0/Neuropeptides; 0/crustacean cardioactive peptide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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