Document Detail

The presence of ochratoxin A in cord serum and in human milk and its correspondence with maternal dietary habits.
MedLine Citation:
PMID:  20812016     Owner:  NLM     Status:  In-Data-Review    
BACKGROUND: Ochratoxin A (OTA) is a mycotoxin present in food that can be found in human blood and milk.
PURPOSE: The link between the nutritional habits of pregnant women both of Italian and foreign nationality resident in Italy and the presence of ochratoxin A in cord blood and in maternal milk was investigated.
METHODS: The study involved 130 pregnant women. Food consumption during pregnancy was evaluated by means of the EPIC questionnaire; OTA content was determined in cord serum and maternal milk by HPLC.
RESULTS: The mean daily dietary intake of OTA was 1.02 ± 1.20 and 0.87 ± 0.78 ng/kg of bodyweight for Italian and non-Italian women, respectively, but this difference was not statistically significant. The incidence of positive milk samples was 73.0 and 85.0% among the Italian and non-Italian mothers, respectively. Pork meat, soft drinks, sweets and red wine showed a significant relationship with OTA level in serum. As far as milk is concerned, a positive relationship resulted for pork meat, sweets, soft drinks and seed oils. A positive relationship between serum OTA level and the ratio serum/milk OTA was found. The intake of OTA had no effect on the cord blood creatinine level.
CONCLUSIONS: This study confirms that OTA is widely present in human milk and therefore could pose a risk for the newborn.
G Biasucci; G Calabrese; R Di Giuseppe; G Carrara; F Colombo; B Mandelli; M Maj; T Bertuzzi; A Pietri; F Rossi
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Publication Detail:
Type:  Journal Article     Date:  2010-09-02
Journal Detail:
Title:  European journal of nutrition     Volume:  50     ISSN:  1436-6215     ISO Abbreviation:  Eur J Nutr     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-04-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100888704     Medline TA:  Eur J Nutr     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  211-8     Citation Subset:  IM    
Department of Pediatrics and Neonatology, Guglielmo da Saliceto Hospital, Cantone del Cristo, 29100, Piacenza, Italy.
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