Document Detail

On the preparation of dihematoporphyrin ether-free hematoporphyrin derivative.
MedLine Citation:
PMID:  2975176     Owner:  NLM     Status:  MEDLINE    
A dihematoporphyrin ether-free hematoporphyrin derivative has been prepared by a base-catalysed dehydration of hematoporphyrin with sodium hydroxide. The identification was performed by HPLC and mass spectroscopy (FD-MS). The reaction of hematoporphyrin with 1 M sodium hydroxide for 24 h yields more than 90% of the monomeric porphyrins.
H Häberlein; P Both; M O Doss
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Biological chemistry Hoppe-Seyler     Volume:  369     ISSN:  0177-3593     ISO Abbreviation:  Biol. Chem. Hoppe-Seyler     Publication Date:  1988 Aug 
Date Detail:
Created Date:  1989-03-02     Completed Date:  1989-03-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8503054     Medline TA:  Biol Chem Hoppe Seyler     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  667-70     Citation Subset:  IM    
Abteilung für Klinische Biochemie im Fachbereich Humanmedizin der Philipps Universität Marburg.
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MeSH Terms
Antineoplastic Agents / chemical synthesis*
Chromatography, High Pressure Liquid
Dihematoporphyrin Ether
Hematoporphyrin Derivative
Hematoporphyrins* / chemical synthesis*,  isolation & purification
Indicators and Reagents
Mass Spectrometry
Reg. No./Substance:
0/Antineoplastic Agents; 0/Hematoporphyrins; 0/Indicators and Reagents; 68335-15-9/Hematoporphyrin Derivative; 97067-70-4/Dihematoporphyrin Ether

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