| Is premature ovarian ageing a cause of unexplained recurrent miscarriage? | |
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MedLine Citation:
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PMID: 22663320 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Recurrent miscarriage is often unexplained. In our study, we test the hypothesis that unexplained recurrent miscarriage is associated with premature ovarian ageing by comparing the basal follicle-stimulating hormone (FSH) level between women with recurrent miscarriage and a control group of subjects in two different ethnic centres: one in Guangzhou, China and the other in Sheffield, UK. The subjects were stratified into three different age groups, and all of them were under the age of 40 years. We found no significant difference in basal FSH level between the subjects and the control groups, and the proportion of women with high FSH (> 10 IU/l) was higher in the Guangzhou cohort but not in the Sheffield cohort. Our observation suggests that premature ovarian ageing is not a significant contributory factor of recurrent miscarriage, but a study on the ethnic variation in the aetiology of recurrent miscarriage is needed. |
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Authors:
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X Yuan; H Y Lin; Q Wang; T C Li |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology Volume: 32 ISSN: 1364-6893 ISO Abbreviation: J Obstet Gynaecol Publication Date: 2012 Jul |
Date Detail:
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Created Date: 2012-06-05 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8309140 Medline TA: J Obstet Gynaecol Country: England |
Other Details:
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Languages: eng Pagination: 464-6 Citation Subset: IM |
Affiliation:
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Reproductive Medicine Centre, Department of Obstetrics and Gynecology of the First Affiliated Hospital of Sun Yat-sen University , Guangzhou , China. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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