Document Detail

A preliminary trial of serratiopeptidase in patients with carpal tunnel syndrome.
MedLine Citation:
PMID:  11225219     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: This study was planned to assess the response of serratiopeptidase in patients with carpal tunnel syndrome (CTS). METHODS: Twenty patients with CTS were evaluated clinically. After baseline electrophysiological studies, these patients were given serratiopeptidase 10 mg twice daily with initial short course of nimesulide. Clinical and electrophysiological reassessment was done after 6 weeks. RESULTS: Mean age was 43.9 years with male to female ratio of 1:2.33. Sixty five percent cases showed significant clinical improvement which was supported by significant improvement in electrophysiological parameters. Recurrence was reported in four cases. No significant side effect was observed. CONCLUSIONS: Serratiopeptidase therapy may proved to be a useful alternative mode of conservative treatment. Larger study may be further helpful to establish the role of serratiopeptidase in CTS.
A Panagariya; A K Sharma
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  The Journal of the Association of Physicians of India     Volume:  47     ISSN:  0004-5772     ISO Abbreviation:  J Assoc Physicians India     Publication Date:  1999 Dec 
Date Detail:
Created Date:  2001-02-27     Completed Date:  2001-03-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7505585     Medline TA:  J Assoc Physicians India     Country:  India    
Other Details:
Languages:  eng     Pagination:  1170-2     Citation Subset:  IM    
Dept. of Neurology, SMS Medical College and Hospital, Jaipur.
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MeSH Terms
Anti-Inflammatory Agents, Non-Steroidal / therapeutic use*
Carpal Tunnel Syndrome / drug therapy*,  physiopathology
Drug Therapy, Combination
Middle Aged
Peptide Hydrolases / therapeutic use*
Severity of Illness Index
Sex Distribution
Sulfonamides / therapeutic use*
Reg. No./Substance:
0/Anti-Inflammatory Agents, Non-Steroidal; 0/Sulfonamides; 51803-78-2/nimesulide; EC 3.4.-/Peptide Hydrolases; EC 3.4.-/serratiopeptidase
Comment In:
J Assoc Physicians India. 2000 Nov;48(11):1130   [PMID:  11310402 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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