Document Detail


A preliminary study of nasal mucociliary clearance in smokers, sinusitis and allergic rhinitis patients.
MedLine Citation:
PMID:  8703239     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Mucocillary clearance of nasal mucosa was evaluated with the saccharin test. A total of 140 subjects was divided into 4 groups: smokers, allergic rhinitis patients, sinusitis patients, and a normal control group. The mean mucociliary transit time for the normal control group (n = 40) was 12 minutes, while allergic rhinitis patients (n = 40) had a mean of 14.6 minutes. The smoker group (n = 40) could be further divided into the following subcategories: (a) those who had been smoking for less than 5 years (n = 10) had a mean of 15.2 minutes, (b) those who had been smoking for more than 5 years at less than one-pack a day (n = 11) had a mean of 14 minutes, and (c) those who had been smoking for more than 5 years at more than one-pack a day (n = 19) had a mean of 16.5 minutes. For the sinusitis patients (n = 20) the mean was 16.6 minutes. The study shows that sinusitis patients, along with those smokers who had been smoking for more than 5 years at more than one-pack a day, had a mucocillary transit time that was considered to be prolonged when compared to the normal control group (p < 0.05).
Authors:
P Mahakit; P Pumhirun
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Asian Pacific journal of allergy and immunology / launched by the Allergy and Immunology Society of Thailand     Volume:  13     ISSN:  0125-877X     ISO Abbreviation:  Asian Pac. J. Allergy Immunol.     Publication Date:  1995 Dec 
Date Detail:
Created Date:  1996-09-12     Completed Date:  1996-09-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8402034     Medline TA:  Asian Pac J Allergy Immunol     Country:  THAILAND    
Other Details:
Languages:  eng     Pagination:  119-21     Citation Subset:  IM    
Affiliation:
Department of Otolaryngology, Pramongkutklao College of Medicine, Bangkok, Thailand.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Female
Humans
Male
Middle Aged
Mucociliary Clearance*
Nasal Mucosa / physiopathology*
Rhinitis / physiopathology*
Saccharin / diagnostic use
Sinusitis / physiopathology*
Smoking / physiopathology*
Chemical
Reg. No./Substance:
81-07-2/Saccharin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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