Document Detail

A preliminary study on the effect of manuka honey on second-intention healing of contaminated wounds on the distal aspect of the forelimbs of horses.
MedLine Citation:
PMID:  22380675     Owner:  NLM     Status:  In-Data-Review    
OBJECTIVE: To determine the effect of manuka honey on second-intention healing of contaminated, full-thickness skin wounds in horses.
STUDY DESIGN: Experimental.
ANIMALS: Adult Standardbred horses (n = 8).
METHODS: One wound was created on the dorsomedial aspect of the third metacarpus in both forelimbs, contaminated with feces, and bandaged for 24 hours. Bandages were removed and wounds rinsed with isotonic saline solution. Wounds on 1 limb had manuka honey applied daily (n = 8) whereas wounds on the contralateral limb received no treatment (n = 8). Bandages were replaced and changed daily for 12 days, after which treatment stopped, bandages were removed, leaving wounds open to heal. Wound area was measured 24 hours after wound creation (day 1), then weekly for 8 weeks. Overall time for healing was recorded. Wound area and rate of healing of treated and control wounds were compared statistically.
RESULTS: Treatment with manuka honey decreased wound retraction and treated wounds remained significantly smaller than control wounds until day 42; however, there was no difference in overall healing time between treatment and control wounds.
CONCLUSIONS: Treatment with manuka honey reduced wound area by reducing retraction but did not affect overall healing time of full-thickness distal limb wounds using this wound-healing model.
Andrea S Bischofberger; Christina M Dart; Nigel R Perkins; Andrew J Dart
Related Documents :
9331035 - Symptomatic venous thromboembolism after total knee replacement.
20103025 - Outcomes for inpatients with normal findings on whole-leg ultrasonography: a prospectiv...
3079005 - Prevention of deep venous thrombosis in orthopedic surgery: effects of defibrotide.
22702195 - Sequential application of nahco3, cacl2 and candida oleophila (isolate 13l) affects sig...
24391075 - Combination ala-pdt and ablative fractional er:yag laser (2,940 nm) on the treatment ...
20014165 - Complications of low-dose, echo-guided alcohol septal ablation.
Publication Detail:
Type:  Journal Article     Date:  2011-09-20
Journal Detail:
Title:  Veterinary surgery : VS     Volume:  40     ISSN:  1532-950X     ISO Abbreviation:  Vet Surg     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2012-03-02     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8113214     Medline TA:  Vet Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  898-902     Citation Subset:  IM    
Copyright Information:
© Copyright 2011 by The American College of Veterinary Surgeons.
Biomedical Research and Clinical Trials Unit, University Veterinary Teaching Hospital, University of Sydney, Camden, Australia.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Effect of experimentally induced synovitis on amikacin concentrations after intravenous regional lim...
Next Document:  Mandibular Fracture in Single-humped Camels.