Document Detail

The pregnancy protecting effect of progesterone against human chorionic gonadotrophin challenge in mares.
MedLine Citation:
PMID:  12277645     Owner:  PIP     Status:  MEDLINE    
14 pregnant Welsh Mountain Pony mares were treated with progesterone in an effort to prevent pregnancy failure induced by administration of human chorionic gonadotropin (GCG). 13 of the 14 mares were treated with progesterone by injection or implant before the 38th day of pregnancy. HCG was given in 3 doses on alternate days at a dose rate of 2000 imc/day. The remaining mare was treated with HCG toward the end of the experiments to demonstrate the abortifacient property of HCG. 3 mares aborted and 1 of these was anovulatory thereafter. Further research is needed to determine the effective progesterone dose and administration regime for mares thought to be suffering from insufficient luteal activity during early pregnancy.
W E Allen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Irish veterinary journal     Volume:  30     ISSN:  0368-0762     ISO Abbreviation:  Ir Vet J     Publication Date:  1976 Feb 
Date Detail:
Created Date:  1980-01-08     Completed Date:  1980-01-08     Revised Date:  2011-06-06    
Medline Journal Info:
Nlm Unique ID:  0100762     Medline TA:  Ir Vet J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  23-7     Citation Subset:  J    
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MeSH Terms
Abortifacient Agents*
Abortion, Induced
Animals, Laboratory*
Chorionic Gonadotropin*
Endocrine System
Family Planning Services
Reg. No./Substance:
0/Abortifacient Agents; 0/Chorionic Gonadotropin; 0/Gonadotropins; 0/Hormones; 0/Progestins; 57-83-0/Progesterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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