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The pregnancy outcome in women with incidental diagnosis of septate uterus at first trimester scan.
MedLine Citation:
PMID:  22752609     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUNDSeptate uterus seems to be strongly associated with an adverse pregnancy outcome. However, the possible relationship between septate uterus and miscarriage has only been retrospectively ascertained. The aim of our study was to describe the reproductive outcome in women with incidental diagnosis of malformed uterus at first trimester scan.METHODSWomen at their first pregnancy attending our centre for a routine viability scan with an incidental suspicion of uterine anomaly at standard sonography were submitted to transvaginal volume ultrasound. All the cases with a 3D diagnosis of septate uterus were prospectively recruited and followed up.RESULTSOverall 24 patients with a single intrauterine pregnancy were included at a median gestational age of 8.2 weeks. The cumulative pregnancy progression rate, as quoted by Kaplan-Meier algorithm, was 33.3% due to the occurrence of early (≤13 weeks) or late miscarriages (14-22 weeks) in 13 and 3 cases, respectively.CONCLUSIONThe pregnancy outcome is poor if a septate uterus is incidentally diagnosed in the early stage of a viable intrauterine pregnancy.
Authors:
Tullio Ghi; Francesca De Musso; Elisa Maroni; Aly Youssef; Luca Savelli; Antonio Farina; Paolo Casadio; Marco Filicori; Gianluigi Pilu; Nicola Rizzo
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-6-29
Journal Detail:
Title:  Human reproduction (Oxford, England)     Volume:  -     ISSN:  1460-2350     ISO Abbreviation:  -     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-7-3     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8701199     Medline TA:  Hum Reprod     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Obstetrics and Gynaecology, St. Orsola Malpighi Hospital, University of Bologna, Bologna, Italy.
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