Document Detail


The predictive value of three diagnostic procedures in the evaluation of palpable breast tumours.
MedLine Citation:
PMID:  6524859     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In a prospective study of 200 palpable breast tumours of 200 women, the diagnostic specificity and sensitivity of clinical examination, mammography, and fine needle aspiration were compared, alone and in combinations. All tumours were excised and examined histologically, and 38 were malignant. The diagnostic sensitivity of clinical examination was high, 98% (91-99), whereas the specificity was rather low, 48% (36-60). No statistically significant differences were found between the sensitivities or the specificities of the three examinations. When the methods were combined the sensitivity was 100% (96-100) and the specificity was 37% (27-46). Statistically, no improvement of the diagnostic value could be shown. It is concluded that the possibility of distinguishing between malignant and benign palpable breast tumours is not increased by adding mammography and/or fine needle aspiration, but the discovery of two non-palpable malignant tumours by mammography underscores the importance of this method in disclosing subclinical malignant lesions. The study disclosed a statistical possibility of overlooking a few malignant tumours when using these three procedures. Therefore, we advise that all palpable breast tumours should be excised.
Authors:
P Crone; J Hertz; T Nilsson; J Junge; K Høier-Madsen; M Kennedy; J Bojsen-Møller; P Diepeveen; A Hahn-Pedersen; S J Jørgensen
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Annales chirurgiae et gynaecologiae     Volume:  73     ISSN:  0355-9521     ISO Abbreviation:  Ann Chir Gynaecol     Publication Date:  1984  
Date Detail:
Created Date:  1985-03-20     Completed Date:  1985-03-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7609767     Medline TA:  Ann Chir Gynaecol     Country:  FINLAND    
Other Details:
Languages:  eng     Pagination:  273-6     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Biopsy, Needle
Breast / pathology
Breast Neoplasms / diagnosis*,  pathology,  radiography
Female
Humans
Mammography
Palpation
Prognosis
Prospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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