Document Detail

The predictive value of additional late blood pool imaging to the three-phase bone scan in the diagnosis of reflex sympathetic dystrophy in hemiplegic patients.
MedLine Citation:
PMID:  15654616     Owner:  NLM     Status:  MEDLINE    
Reflex sympathetic dystrophy (RSD) is a relative common sequel after hemiplegia. The diagnosis of RSD in hemiplegic patients presents difficult clinical problems, as the symptoms and signs of RSD are not specific and RSD may be due to reasons other than hemiplegia. Bone scintigraphy has been routinely used for the diagnosis of RSD; however, the optimal acquisition protocols, diagnostic patterns and the utility of quantitation are controversial. This prospective study was conducted to demonstrate the higher predictive value of an additional late blood pool image to the three-phase bone scan compared to the regular three-phase bone scans in RSD patients associated with hemiplegia. Thirty-four RSD patients were enrolled into the study. Bone scans according to the new protocol were obtained for all patients. Those patients with either negative or positive bone scans with no evidence of RSD were followed for 6 months. The patients had positive bone scan findings and were symptomatic at the time of the study. Of these, seven patients (58.3%) subsequently became symptomatic and five patients (41.7%) remained asymptomatic at 6 months. None of the patients with negative bone scans had symptoms of RSD on presentation except one case. We conclude that the addition of a late blood pool image increases the predictive value and has an impact on initiating early treatment in asymptomatic patients.
Berna Okudan; Canan Celik; Seyfi Serttas; Ne?e Ozgirgin
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article     Date:  2005-01-15
Journal Detail:
Title:  Rheumatology international     Volume:  26     ISSN:  0172-8172     ISO Abbreviation:  Rheumatol. Int.     Publication Date:  2005 Dec 
Date Detail:
Created Date:  2005-12-12     Completed Date:  2006-09-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8206885     Medline TA:  Rheumatol Int     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  126-31     Citation Subset:  IM    
Nuclear Medicine Department, Ankara Numune Research and Training Hospital, 104 Isparta, Turkey.
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MeSH Terms
Blood Flow Velocity
Bone and Bones / radionuclide imaging*
Hemiplegia / complications,  physiopathology,  radionuclide imaging*
Predictive Value of Tests
Prospective Studies
Radionuclide Angiography / methods*
Reflex Sympathetic Dystrophy / complications,  physiopathology,  radionuclide imaging*
Upper Extremity / blood supply,  pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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