| A predictive score for retinopathy of prematurity in very low birth weight preterm infants. | |
| | |
MedLine Citation:
|
PMID: 22193874 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
AIMS: This study describes the development of a score based on cumulative risk factors for the prediction of severe retinopathy of prematurity (ROP) comparing the performance of the score against the birth weight (BW) and gestational age (GA) in order to predict the onset of ROP. METHODS: A prospective cohort of preterm infants with BW≤ 1500 g and/or GA≤ 32 weeks was studied. The score was developed based on BW, GA, proportional weight gain from birth to the 6th week of life, use of oxygen in mechanical ventilation, and need for blood transfusions from birth to the 6th week of life. The score was established after linear regression, considering the impact of each variable on the occurrences of any stage and severe ROP. Receiver operating characteristic (ROC) curves were used to determine the best sensitivity and specificity values for the score. All variables were entered into an Excel spreadsheet (Microsoft) for practical use by ophthalmologists during screening sessions. RESULTS: The sample included 474 patients. The area under the ROC curve for the score was 0.77 and 0.88 to predict any stage and severe ROP, respectively. These values were significantly higher for the score than for BW (0.71) and GA (0.69) when measured separately. CONCLUSIONS: ROPScore is an excellent index of neonatal risk factors for ROP, which is easy to record and more accurate than BW and GA to predict any stage ROP or severe ROP in preterm infants. The scoring system is simple enough to be routinely used by ophthalmologists during screening examination for detection of ROP. |
| | |
Authors:
|
G U Eckert; J B Fortes Filho; M Maia; R S Procianoy |
Related Documents
:
|
22647744 - Cdc grand rounds: newborn screening and improved outcomes. 21828164 - Birth outcomes among booked and unbooked women at a secondary health facility in southw... 22000304 - Elevated concentrations of inflammation-related proteins in postnatal blood predict sev... 6886914 - Diagnosis of hereditary spherocytosis in newborn infants. 3372284 - Anthropometric predictors of low birth weight outcome in teenage pregnancy. 2327444 - Neonatal growth assessment score: a new approach to the detection of intrauterine growt... |
Publication Detail:
|
Type: Journal Article Date: 2011-12-23 |
Journal Detail:
|
Title: Eye (London, England) Volume: 26 ISSN: 1476-5454 ISO Abbreviation: Eye (Lond) Publication Date: 2012 Mar |
Date Detail:
|
Created Date: 2012-03-08 Completed Date: 2012-05-02 Revised Date: 2013-04-15 |
Medline Journal Info:
|
Nlm Unique ID: 8703986 Medline TA: Eye (Lond) Country: England |
Other Details:
|
Languages: eng Pagination: 400-6 Citation Subset: IM |
Affiliation:
|
Department of Ophthalmology, Federal University of Rio Grande do Sul, Brazil. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Female Gestational Age Humans Infant, Newborn Infant, Premature Infant, Very Low Birth Weight* Male Predictive Value of Tests Prospective Studies ROC Curve Regression Analysis Retinopathy of Prematurity / diagnosis* Risk Factors Sensitivity and Specificity Severity of Illness Index* |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Superior semicircular canal dehiscence syndrome as assessed by oVEMP and temporal bone computed tomo...
Next Document: Optical coherence tomography changes before the development of choroidal neovascularization in secon...