| The predictive role of HbA₁(c) and previous medications in initiation of insulin treatment. | |
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MedLine Citation:
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PMID: 21055372 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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INTRODUCTION: Subjects (n = 46) with type 2 diabetes who responded inadequately to two and three oral medications (HbA₁(C) > 8.0%) were consecutively recruited for treatment with premixed insulin 30/70 two times a day in order to investigate whether previous oral therapies may predict insulin requirements. MATERIAL AND METHODS: In this prospective study, men and women were eligible to participate if they were aged between 30 and 65 years, had had a diagnosis of type 2 diabetes mellitus for at least 12 months, were insulin-naive and had been treated unsuccessfully with either two or three oral antidiabetic drugs for a minimum of three months. Clinical and laboratory findings were analyzed at one year follow-up. RESULTS: The average required insulin doses were significantly higher in patients in whom previous triple oral medication had failed than in patients in whom two oral drugs had failed. CONCLUSION: Evaluation of the previous number of oral antidiabetic drugs and HbA₁(C) values may help us predict the insulin requirement when oral drugs have failed. |
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Authors:
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Hakan Demirci; Yildirim Cinar |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Danish medical bulletin Volume: 57 ISSN: 1603-9629 ISO Abbreviation: Dan Med Bull Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-11-08 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0066040 Medline TA: Dan Med Bull Country: Denmark |
Other Details:
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Languages: eng Pagination: A4214 Citation Subset: IM |
Affiliation:
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Nilüfer Toplum SağlIğI Merkezi, Department of Family Medicine, Turkey. drhakandemirci@hotmail.com |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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