Document Detail


The prediction of papaverine induced priapism by color Doppler sonography.
MedLine Citation:
PMID:  11176386     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: We identified color Doppler sonography findings that are useful for predicting priapism in patients after the intracavernous injection of diagnostic papaverine. MATERIALS AND METHODS: We evaluated 72 men with erectile dysfunction by color Doppler sonography after the diagnostic injection of papaverine. Cavernous artery waveforms were recorded, and peak systolic and diastolic velocity of the recorded waveforms was measured. In cases of priapism color Doppler sonography findings were retrospectively evaluated to identify any finding that would predict priapism. RESULTS: Priapism was observed in 8 of the 72 patients (11.1%). In 6 of 8 priapism cases there was no blood flow in the cavernous artery during or after adequate erection, including after minutes 5, 10 and 20 in 3, 1 and 2, respectively. This absence of encoding was not relieved even after all stimuli were removed. In 2 patients who later presented with complaints of priapism the Doppler study was completed normally and all parameters were acquired without any cessation of blood flow in the cavernous artery. The persistent disappearance of color and pulse encoding in the cavernous artery predicted priapism with 75% sensitivity, 100% specificity, a positive and negative predictive value of 100% and 96.9%, respectively, and 97% accuracy. CONCLUSIONS: The persistence of absent blood flow in the cavernous artery even after the elimination of all stimuli during penile color Doppler ultrasound is a reliable predictor of priapism. The finding is accurate enough to initiate treatment for priapism to avoid further delay.
Authors:
M Secil; D Arslan; A Y Goktay; A A Esen; O Dicle; T Pirnar
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of urology     Volume:  165     ISSN:  0022-5347     ISO Abbreviation:  J. Urol.     Publication Date:  2001 Feb 
Date Detail:
Created Date:  2001-02-22     Completed Date:  2001-05-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0376374     Medline TA:  J Urol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  416-8     Citation Subset:  AIM; IM    
Affiliation:
Departments of Radiology and Urology, Dokuz Eylul University Hospital, Izmir, Turkey.
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MeSH Terms
Descriptor/Qualifier:
Humans
Male
Papaverine / adverse effects*,  diagnostic use
Predictive Value of Tests
Priapism / chemically induced*
Retrospective Studies
Ultrasonography, Doppler, Color*
Vasodilator Agents / adverse effects*,  diagnostic use
Chemical
Reg. No./Substance:
0/Vasodilator Agents; 58-74-2/Papaverine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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