Document Detail


A practical route to tertiary diarylmethylamides or -carbamates from imines, organozinc reagents and acyl chlorides or chloroformates.
MedLine Citation:
PMID:  21915199     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
A practical route to tertiary diarylmethylamides or -carbamates from imines, organozinc reagents and acyl chlorides or chloroformates is described. This route involves the formation of an imine, which is used without isolation, followed by its activation by the carbonyl-containing electrophile and the trapping of the acyliminium by an organozinc reagent. Most steps are conducted concomitantly to render the procedure as practical and straightforward as possible. Therefore, the whole experimental protocol takes less than two hours.
Authors:
Erwan Le Gall; Antoine Pignon; Thierry Martens
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Publication Detail:
Type:  Journal Article     Date:  2011-07-20
Journal Detail:
Title:  Beilstein journal of organic chemistry     Volume:  7     ISSN:  1860-5397     ISO Abbreviation:  Beilstein J Org Chem     Publication Date:  2011  
Date Detail:
Created Date:  2011-09-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101250746     Medline TA:  Beilstein J Org Chem     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  997-1002     Citation Subset:  -    
Affiliation:
Électrochimie et Synthèse Organique, Institut de Chimie et des Matériaux Paris-Est, UMR 7182 CNRS - Université Paris-Est Créteil, 2-8 rue Henri Dunant, 94320 Thiais, France.
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