Document Detail


A practical approach to gout. Current management of an 'old' disease.
MedLine Citation:
PMID:  10533512     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Gouty arthritis is the culmination of a number of physiologic mechanisms that ultimately result in deposition of uric acid within joints and soft tissues. Decreased uric acid clearance through the kidney is the most common cause of gout. Tophaceous gout occurs in less than 10% of patients. Acute episodes are treated with NSAIDs or colchicine. Low-dose therapy with these agents can also prevent recurrent attacks. Most patients with gout need long-term treatment with either uricosuric agents or xanthine oxidase inhibitors.
Authors:
J C Davis
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Postgraduate medicine     Volume:  106     ISSN:  0032-5481     ISO Abbreviation:  Postgrad Med     Publication Date:  1999 Oct 
Date Detail:
Created Date:  1999-11-12     Completed Date:  1999-11-12     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0401147     Medline TA:  Postgrad Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  115-6, 119-23     Citation Subset:  AIM; IM    
Affiliation:
Division of Rheumatology, UCSF 94143-0633, USA. jdavis@medicine.ucsf.edu
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MeSH Terms
Descriptor/Qualifier:
Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
Arthritis, Gouty / drug therapy*,  etiology
Colchicine / therapeutic use
Glucocorticoids / therapeutic use
Humans
Uricosuric Agents / therapeutic use
Xanthine Oxidase / antagonists & inhibitors
Chemical
Reg. No./Substance:
0/Anti-Inflammatory Agents, Non-Steroidal; 0/Glucocorticoids; 0/Uricosuric Agents; 64-86-8/Colchicine; EC 1.17.3.2/Xanthine Oxidase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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