| The potential to improve diabetes control with vitamin D replacement in African American patients: case report and literature review. | |
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MedLine Citation:
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PMID: 20481247 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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African Americans have a higher prevalence of Diabetes mellitus and associated complications. The prevalence of Vitamin D deficiency is also higher in African Americans. We report an African American veteran who was followed for a period of 10 years in the Endocrine clinic for insulin-requiring diabetes. Despite intensive, medical, nutritional and educational efforts during that period, no discernible progress was made in achieving any improvement in glycemic control. The patient appeared to be noncompliant with recommended strategies to improve glycemia. The patient was seen recently and was found to be profoundly Vitamin D deficient with a 25 (OH) Vitamin D level of 11.6 ng/ml [30-100 ng/ml]. While patient did not wish to change his insulin regimen or diabetic management, he was willing to accept Vitamin D therapy. Replacement with Vitamin D was associated with significant improvement in glycosylated hemoglobin to previously unmatched levels of glycemic control. We discuss the multiple potential mechanisms by which improved Vitamin D status may result in improved diabetes control. Given the current pandemic of Vitamin D deficiency and the plethora of potential benefits, we recommend maintaining adequate Vitamin D reserves in diabetic patients with a special emphasis on minority populations. |
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Authors:
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Dima Youssef; Adel El Abbassi; Kelli Jones; Garren Woodby; Alan Peiris |
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Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: Tennessee medicine : journal of the Tennessee Medical Association Volume: 103 ISSN: 1088-6222 ISO Abbreviation: Tenn Med Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-05-20 Completed Date: 2010-06-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9609310 Medline TA: Tenn Med Country: United States |
Other Details:
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Languages: eng Pagination: 35-6 Citation Subset: IM |
Affiliation:
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East Tennessee State University, Mountain Home VAMC, Johnson City, TN 37614, USA. estecina@hotmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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African Americans Aged Diabetes Mellitus, Type 2 / prevention & control* Ergocalciferols / therapeutic use* Humans Male Vitamin D Deficiency / drug therapy* |
| Chemical | |
Reg. No./Substance:
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0/Ergocalciferols |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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