Document Detail

The potential role of the pericardium on diastolic filling in endurance-trained athletes under conditions of physiological stress.
MedLine Citation:
PMID:  17486175     Owner:  NLM     Status:  MEDLINE    
In this review, we examine the growing body of evidence suggesting that the pericardium plays an important role in modulating cardiac function during conditions of physiological stress. Specifically, we discuss the effects of the pericardium on left ventricular filling and compliance. Furthermore, we reveal that there is increasing evidence to support the contention that the pericardium is capable of adaptation in response to volume loading. We also provide data that suggests endurance-training is a good example of a physiological stressor capable of causing pericardial remodelling. These adaptations appear particularly beneficial during exercise and may explain (in part) the common finding of stroke volume increasing during exercise to a greater extent in endurance-trained athletes. However, this adaptation may also partially explain the increased susceptibility to orthostatic intolerance in endurance athletes.
Ben T A Esch; Shannon S D Bredin; Mark J Haykowsky; Jessica M Scott; Darren E R Warburton
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Applied physiology, nutrition, and metabolism = Physiologie appliquée, nutrition et métabolisme     Volume:  32     ISSN:  1715-5312     ISO Abbreviation:  -     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-05-08     Completed Date:  2007-06-29     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  101264333     Medline TA:  Appl Physiol Nutr Metab     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  311-7     Citation Subset:  IM    
Cardiovascular Physiology and Rehabilitation Laboratory, University of British Columbia, 6108 Thunderbird Blvd., Rm. 205, Unit II Osborne Centre, Vancouver, BC V6T 1Z3, Canada.
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MeSH Terms
Cardiac Volume / physiology*
Physical Education and Training
Physical Endurance / physiology*
Physical Fitness / physiology*
Stress, Physiological*
Ventricular Function, Left*

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