| The potential role of leptin and adiponectin in obesity: A comparative review. | |
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MedLine Citation:
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PMID: 21592831 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Leptin and adiponectin are adipokines produced by the white adipose tissue. The adipokines have been shown to be valuable quantitative markers of adiposity in dogs. Leptin positively correlates with body condition score (BCS) in dogs, regardless of age, sex and breed, and is influenced by feeding state, pharmacological treatment and thyroid gland activity. Conversely, adiponectin negatively correlates with body fat mass and is therefore more abundant in lean animals. The implication of leptin and adiponectin in the pathogenesis of metabolic syndrome is well established in humans, but currently lacking in dogs. Additional studies are necessary to demonstrate their potential usefulness for monitoring the progression of obesity-related diseases and response to treatment. To date, measurement of canine leptin and adiponectin has been used in experimental studies only, whereas bodyweight and BCS are considered the first-approach parameters for the routine assessment of body fat content in obese dogs. |
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Authors:
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Rebecca Ricci; Francesca Bevilacqua |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-5-16 |
Journal Detail:
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Title: Veterinary journal (London, England : 1997) Volume: - ISSN: 1532-2971 ISO Abbreviation: - Publication Date: 2011 May |
Date Detail:
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Created Date: 2011-5-19 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9706281 Medline TA: Vet J Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 Elsevier Ltd. All rights reserved. |
Affiliation:
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Department of Animal Science, University of Padua, Viale dell'Università 12 and 16, 35020 Legnaro (PD), Italy. |
Export Citation:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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