Document Detail

The potential power output for skeletal muscle to provide cardiac assistance.
MedLine Citation:
PMID:  2049444     Owner:  NLM     Status:  MEDLINE    
It is clear that autologous skeletal muscle offers a potential power source, free of invasive tubes and wires and without the need for immunosuppressive or antibiotic therapy, with the capability of assuming at least 25% to 50% of the natural heart's workload. The application of this power source as either a heart wrap in CMP procedures or as an assist ventricle in SMV designs is not only possible, but in fact, reality in the case of CMP procedures. Optimization of these applications requires continued research, but offers renewed hope for patients with CHF who currently depend on indefinite pharmacologic therapy, the total artificial heart, or the too few donor hearts for transplantation.
S F Badylak
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Publication Detail:
Type:  In Vitro; Journal Article; Review    
Journal Detail:
Title:  Seminars in thoracic and cardiovascular surgery     Volume:  3     ISSN:  1043-0679     ISO Abbreviation:  Semin. Thorac. Cardiovasc. Surg.     Publication Date:  1991 Apr 
Date Detail:
Created Date:  1991-07-25     Completed Date:  1991-07-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8917640     Medline TA:  Semin Thorac Cardiovasc Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  116-8     Citation Subset:  IM    
Hillenbrand Biomedical Engineering Center, Purdue University, W Lafayette, IN 47907.
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MeSH Terms
Cardiac Surgical Procedures*
Electric Stimulation
Heart-Assist Devices
Muscle Contraction
Muscles / transplantation*
Myocardial Contraction*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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