Document Detail


The potential impact of new donor height and weight criteria on young donor eligibility and faint or prefaint reaction rates.
MedLine Citation:
PMID:  21496042     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
BACKGROUND: New criteria for young blood donors were recently developed to minimize faint reactions in this high-risk group. The aim of this study was to determine the impact implementation of these criteria would have on collections and donor faint or prefaint reaction rates at our university blood center.
STUDY DESIGN AND METHODS: Donor history questionnaires from eight consecutive undergraduate campus blood drives were retrospectively reviewed. Height, weight, sex, and age were used to determine the number of donors potentially deferred.
RESULTS: During the study period, 81% of donors were age 22 or younger (537/662) with a reaction rate of 2.4% (16/662). If these new height and weight criteria were implemented, 11.5% of our young donors would have been deferred (76/662) preventing 2 of 16 reactions. Revision of height and weight criteria with consideration for a 475-mL collection volume would decrease deferral rates to 1.2% (8/662) with no reactions prevented.
CONCLUSION: Implementation of new height and weight criteria based on a standard 525-mL collection volume would result in a high rate of donor deferral. Revised criteria adjusted for our smaller collection volume would significantly decrease donor deferral rates. All reactions observed in young donors during our study period occurred in those predicted to have a less than 15% decrease in total blood volume after donation.
Authors:
Nancy Dunbar; Jean Katz; Ashok Nambiar
Publication Detail:
Type:  Journal Article     Date:  2010-10-26
Journal Detail:
Title:  Transfusion     Volume:  51     ISSN:  1537-2995     ISO Abbreviation:  Transfusion     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-04-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0417360     Medline TA:  Transfusion     Country:  United States    
Other Details:
Languages:  eng     Pagination:  737-41     Citation Subset:  IM    
Copyright Information:
© 2010 American Association of Blood Banks.
Affiliation:
From the Department of Laboratory Medicine, University of California at San Francisco, San Francisco, California.
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