| A potential fortuitous binding of inhibitors of an inverting family GH9 β-glycosidase derived from isofagomine. | |
| | |
MedLine Citation:
|
PMID: 21785782 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Using structural insight, the binding mode of isofagomine-derived inhibitors with family GH9 glycosidases is achieved via the study of Alicyclobacillus acidocaldarius (AaCel9A) endoglucanase. In contrast to what was observed in the first report using these compounds with inverting glycosidases from family GH6, these inhibitors do not adopt a distorted conformation in the active site. |
| | |
Authors:
|
Solange Moréra; Armelle Vigouroux; Keith A Stubbs |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-7-25 |
Journal Detail:
|
Title: Organic & biomolecular chemistry Volume: - ISSN: 1477-0539 ISO Abbreviation: - Publication Date: 2011 Jul |
Date Detail:
|
Created Date: 2011-7-25 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101154995 Medline TA: Org Biomol Chem Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Laboratoire d'Enzymologie et Biochimie Structurales (LEBS), CNRS, Avenue de la Terrasse, 91198, Gif-sur-Yvette, France. morera@lebs.cnrs-gif.fr. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Ti(iv) doped WO(3) nanocuboids: fabrication and enhanced visible-light-driven photocatalytic perform...
Next Document: 3-Substituted-2,4-pentanedionates: ligands for photoactive supramolecular assemblies.