| The potential applications of high-intensity focused ultrasound (HIFU) in vascular neurosurgery. | |
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MedLine Citation:
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PMID: 22169506 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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This review assesses the feasibilty of high-intensity focused ultrasound (HIFU) in neurosurgical applications, specifically occlusion of intact blood vessels. Fourteen articles were examined. In summary, MRI was effective for HIFU guidance whereas MR angiography assessed vessel occlusion. Several studies noted immediate occlusion of blood vessels with HIFU. Long-term data, though scarce, indicated a trend of vessel recanalization and return to pre-treatment diameters. Effective parameters for extracranial vascular occlusion included intensity ranges of 1690-8800W/cm(2), duration <15seconds, and 0.68-3.3MHz frequency. A threshold frequency-intensity product of 8250MHzW/cm(2) was needed for vascular occlusion with a sensitivity of 70% and a specificity of 86%. Complications include skin burns, hemorrhage, and damage to surrounding structures. With evidence that HIFU can successfully occlude extracranial blood vessels, refinement in applications and demonstrable intracranial occlusion are needed. |
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Authors:
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Joseph Serrone; Hasan Kocaeli; T Douglas Mast; Mark T Burgess; Mario Zuccarello |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-12-12 |
Journal Detail:
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Title: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia Volume: - ISSN: 1532-2653 ISO Abbreviation: - Publication Date: 2011 Dec |
Date Detail:
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Created Date: 2011-12-15 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9433352 Medline TA: J Clin Neurosci Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 Elsevier Ltd. All rights reserved. |
Affiliation:
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Department of Neurosurgery, University of Cincinnati Neuroscience Institute and UC College of Medicince, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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