| A postmortem quantitative study of iron in the globus pallidus of schizophrenic patients. | |
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MedLine Citation:
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PMID: 2294978 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Several postmortem studies have reported the presence and probable overabundance of basal ganglia mineralization in schizophrenic patients. In order to study this problem in a quantitative fashion we analyzed the mineral content of the globus pallidus in 9 schizophrenic patients and 10 age-matched controls with a Loats computer image analysis system. No significant differences were noted between schizophrenic patients and controls in regard to gender, age, or mineral content of the globus pallidus. The mean content of iron per internal segment of globus pallidus was greater in schizophrenic patients, but the large variation and small number of patients in our sample may have accounted for the negative findings. |
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Authors:
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M F Casanova; I N Waldman; J E Kleinman |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Biological psychiatry Volume: 27 ISSN: 0006-3223 ISO Abbreviation: Biol. Psychiatry Publication Date: 1990 Jan |
Date Detail:
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Created Date: 1990-02-22 Completed Date: 1990-02-22 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0213264 Medline TA: Biol Psychiatry Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 143-9 Citation Subset: IM |
Affiliation:
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Clinical Brain Disorders Branch, National Institute of Mental Health, Washington, D.C. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Female Globus Pallidus / metabolism* Humans Image Processing, Computer-Assisted Iron / metabolism* Male Middle Aged Retrospective Studies Schizophrenia / metabolism* Signal Processing, Computer-Assisted |
| Chemical | |
Reg. No./Substance:
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7439-89-6/Iron |
| Comments/Corrections | |
Comment In:
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Biol Psychiatry. 1991 Feb 1;29(3):296-7
[PMID:
2015334
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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