Document Detail


A posteriori-derived dietary patterns and retinal vessel caliber in an elderly population.
MedLine Citation:
PMID:  23322577     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To examine the association between a posteriori-derived dietary patterns (DP) and retinal vessel caliber in an elderly population.
METHODS: This was a cross-sectional study of 288 elderly adults (>65 years) who participated in the European Eye study (EUREYE) Northern Irish cohort. DP were extracted using principal component analysis from completed food frequency questionnaires. Semi-automated computer grading was used to determine the mean retinal vessel diameters (central retinal arteriole equivalent [CRAE] and central retinal venule equivalent [CRVE]) from digitized visual field one images using a standard measurement protocol.
RESULTS: THREE MAJOR DP WERE IDENTIFIED IN THIS POPULATION, WHICH ACCOUNTED FOR 21% OF THE TOTAL VARIANCE: a "healthy" pattern with high factor loadings for oily fish, fruits and vegetables, and olive oil; an "unhealthy" pattern with high factor loadings for red and processed meat, refined grains, eggs, butter, sugar and sweets; and a "snack and beverage" pattern with high factor loading for pizza, nuts, and coffee. Multivariable linear regression analysis indicated no significant association between major identified DP and mean CRAE or CRVE in all models.
CONCLUSIONS: This is the first study to investigate associations between a posteriori-derived DP and retinal vessel caliber. There was no evidence of a relationship between extracted DP and retinal vessel measurements in this population. However, it is possible that potentially important relationships exist between single nutrients or foods and vessel diameters that cannot be identified using a DP approach. Further studies to examine the role of dietary factors in the microcirculation are required.
Authors:
Claire T McEvoy; Christopher R Cardwell; Usha Chakravarthy; Ruth E Hogg; Michelle C McKinley; Ian S Young; Astrid E Fletcher; Jayne V Woodside
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Publication Detail:
Type:  Comparative Study; Journal Article; Multicenter Study     Date:  2013-02-15
Journal Detail:
Title:  Investigative ophthalmology & visual science     Volume:  54     ISSN:  1552-5783     ISO Abbreviation:  Invest. Ophthalmol. Vis. Sci.     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-02-18     Completed Date:  2013-04-09     Revised Date:  2013-08-08    
Medline Journal Info:
Nlm Unique ID:  7703701     Medline TA:  Invest Ophthalmol Vis Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1337-44     Citation Subset:  IM    
Affiliation:
Centre for Public Health, School of Medicine, Dentistry & Biomedical Sciences, Queen’s University Belfast, Institute of Clinical Science B (FirstFloor), Grosvenor Road, Belfast, UK.
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MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Aging*
Cross-Sectional Studies
Female
Food Habits*
Humans
Male
Questionnaires
Retinal Vessels / pathology*

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