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The posterior reversible encephalopathy syndrome: what's certain, what's new?
MedLine Citation:
PMID:  21551107     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The posterior reversible encephalopathy syndrome is an increasingly recognised disorder. Most patients have several symptoms; seizures are the most frequent, often multiple or status epilepticus. A combination of seizures, visual disturbance and/or headache, in particular, should lead to an early brain MRI to reveal the typical pattern of bilateral hyperintensities on fluid attenuated inversion recovery imaging, predominantly in the parieto-occipital region. There seem to be many possible triggers, including abrupt arterial hypertension, impaired renal function, pregnancy, immunosuppressive therapies and various inflammatory conditions. The clinical outcome is excellent, with recovery within a few days, while the MRI abnormalities resolve much more slowly. Little is known about the best management. Seizures do not normally progress to chronic epilepsy so antiepileptic drugs should be discontinued after about 3 months.
Authors:
C Roth; A Ferbert
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Practical neurology     Volume:  11     ISSN:  1474-7766     ISO Abbreviation:  Pract Neurol     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-05-09     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101130961     Medline TA:  Pract Neurol     Country:  England    
Other Details:
Languages:  eng     Pagination:  136-44     Citation Subset:  IM    
Affiliation:
Consultant Neurologist, Head of the Neuro-Intensive Care Unit, Department of Neurology, Klinikum Kassel, Kassel, Germany.
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