| The post-thrombotic syndrome - a condition to prevent. | |
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MedLine Citation:
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PMID: 18627714 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The incidence of the post-thrombotic syndrome (PTS) is increasing along with the incidence of deep vein thrombosis (DVT). The overall frequency of PTS ranges from 20 percent to 50 percent of DVT patients; severe PTS, which includes leg ulcers, occurs in a quarter of cases. Because of its severity and chronicity, PTS is associated with great morbidity and cost. Its diagnosis is primarily based on the presence of typical symptoms and signs, but objective evidence of venous valvular reflux can help to confirm the diagnosis. Because therapeutic options for PTS are extremely limited and results are often disappointing, prevention, recognition of clinical signs or complications, and early treatment remain the keys to reducing its morbidity. The prevention of DVT recurrence by anticoagulation and use of graduated compression stockings is likely to reduce the risk of PTS. There is no proven role for thrombolysis in preventing PTS. |
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Authors:
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Delphine Pirard; Bernard Bellens; Pierre Vereecken |
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Publication Detail:
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Type: Journal Article; Review Date: 2008-03-15 |
Journal Detail:
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Title: Dermatology online journal Volume: 14 ISSN: 1087-2108 ISO Abbreviation: Dermatol. Online J. Publication Date: 2008 |
Date Detail:
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Created Date: 2008-07-16 Completed Date: 2008-09-24 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9610776 Medline TA: Dermatol Online J Country: United States |
Other Details:
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Languages: eng Pagination: 13 Citation Subset: IM |
Affiliation:
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Department of Dermatology, Erasme hospital, Université Libre de Bruxelles Brussels, Belgium. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anticoagulants
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therapeutic use Erysipelas / etiology, pathology Humans Leg Dermatoses / etiology, pathology Lymphangiosarcoma / etiology Lymphedema / etiology, pathology Postthrombotic Syndrome* / diagnosis, etiology, prevention & control Skin / pathology* Skin Care Skin Neoplasms / etiology Stockings, Compression Venous Thrombosis / complications*, therapy |
| Chemical | |
Reg. No./Substance:
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0/Anticoagulants |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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