Document Detail


The possible roles of water in the prebiotic chemical evolution of DNA.
MedLine Citation:
PMID:  20577681     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
There is no doubt that water is pivotal to life. Yet, as the emergence of life is still a big challenge in science, the detailed involvement of water in that process is not well recognized. Following the clues provided by recent single-molecule studies on DNA, we attempt to elucidate the possible roles of water in the prebiotic chemical evolution. Water has long been recognized as an important reactant in the Miller-Urey experiment and then as the only solvent of the primitive soup. Besides that, water also played a vital role in the prebiotic chemical evolution: water is the important criterion in the combinatorial library screening for self-assembling macromolecules. With this notion, the uniformity of biochemistry for all terrestrial life may be explained. A possible roadmap from the inorganic world to the origin of life is also discussed.
Authors:
Shuxun Cui
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2010-06-24
Journal Detail:
Title:  Physical chemistry chemical physics : PCCP     Volume:  12     ISSN:  1463-9084     ISO Abbreviation:  Phys Chem Chem Phys     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-08-27     Completed Date:  2010-12-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100888160     Medline TA:  Phys Chem Chem Phys     Country:  England    
Other Details:
Languages:  eng     Pagination:  10147-53     Citation Subset:  IM    
Affiliation:
Key Laboratory of Advanced Technologies of Materials, Southwest Jiaotong University, Chengdu 610031, China. cuishuxun@swjtu.edu.cn
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MeSH Terms
Descriptor/Qualifier:
Adaptation, Physiological
DNA / chemistry*
Evolution, Chemical*
Prebiotics*
Water / chemistry*
Chemical
Reg. No./Substance:
0/Prebiotics; 7732-18-5/Water; 9007-49-2/DNA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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