| The possible role of hyperhomocysteinemia on IVF outcome. | |
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MedLine Citation:
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PMID: 17763935 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To evaluate the effect of the hyperhomocysteinemia on pregnancy rate, implantation rate and abortion rate after IVF. METHOD: Data from a total of 48 infertile couples with hyperhomocysteinemia were prospectively collected for this study. All patients underwent a standard down regulation protocol for ovarian stimulation. Oocytes recovery was performed at 36 h after hCG administration. Embryo transfer took place at 48 h after insemination. The patients were matched in two groups that received or did not receive therapy (group A and B respectively) to normalize homocysteine plasma level. RESULTS: Pregnancy rate, implantation rate and abortion rate varied significantly (p<or=0.05) between the two groups. The number and quality of embryos transferred did not differ between the groups. CONCLUSION: The results suggest that hyperhomocysteinemia could affect IVF outcome. |
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Authors:
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Arianna Pacchiarotti; Mohamed A Mohamed; Giulietta Micara; Antonella Linari; Daniela Tranquilli; Salomè B Espinola; Cesare Aragona |
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Publication Detail:
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Type: Journal Article Date: 2007-09-01 |
Journal Detail:
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Title: Journal of assisted reproduction and genetics Volume: 24 ISSN: 1058-0468 ISO Abbreviation: J. Assist. Reprod. Genet. Publication Date: 2007 Oct |
Date Detail:
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Created Date: 2007-10-29 Completed Date: 2008-01-14 Revised Date: 2013-03-13 |
Medline Journal Info:
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Nlm Unique ID: 9206495 Medline TA: J Assist Reprod Genet Country: United States |
Other Details:
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Languages: eng Pagination: 459-62 Citation Subset: IM |
Affiliation:
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Obstetric and Gynecology, Policlinico Umberto, La Sapienza University of Rome, Viale Regina Elena, Rome, Italy. arypac@aliceposta.it |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abortion, Spontaneous
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etiology* Adult Embryo Implantation* Female Fertilization in Vitro* Humans Hyperhomocysteinemia / complications* Pregnancy Pregnancy Outcome Pregnancy Rate* |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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