Document Detail

The possible prognostic usefulness of assessing serum proteins and cholesterol in malignancy.
MedLine Citation:
PMID:  1167805     Owner:  NLM     Status:  MEDLINE    
Serial measurement of serum proteins, albumin, and cholesterol levels was used in attempt to assess the course and prognosis in cancer patients. This assessment is based on the fact that their declines followed first order kinetics and that these patients usually died when their levels were lower than half the initial levels. Two categories of cancer patients were identified: those in whom the initial measurements of serum albumin or cholersterol, taken soon after diagnosis, were declining (Group I), and those who showed such a decline as they entered an advanced or terminal phase (Group II). Group I included cancer of the stomach, kidney, lung (adenocarcinoma and squamous cell carcinoma), oral cavity, large intestine, breast (40%), bladder, ovary (70%), pancreas, and prostate; leukemia (acute myeloid and lymphocytic); and Hodgkin's disease (60%), all of which accounted for approximately 90% of the major causes of cancer deaths. Group II included Hodgkin's disease (40%), and cancer of the ovary (30%) and breast (60%), all of which accounted for 10% of the major causes of cancer deaths.
F C Chao; B Efron; P Wolf
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cancer     Volume:  35     ISSN:  0008-543X     ISO Abbreviation:  Cancer     Publication Date:  1975 Apr 
Date Detail:
Created Date:  1975-06-12     Completed Date:  1975-06-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0374236     Medline TA:  Cancer     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1223-9     Citation Subset:  AIM; IM    
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MeSH Terms
Adenocarcinoma / blood
Blood Proteins*
Breast Neoplasms / blood
Carcinoma, Squamous Cell / blood
Cholesterol / blood*
Hodgkin Disease / blood
Intestinal Neoplasms / blood
Kidney Neoplasms / blood
Leukemia / blood
Lung Neoplasms / blood
Mouth Neoplasms / blood
Neoplasms / blood*,  mortality
Ovarian Neoplasms / blood
Pancreatic Neoplasms / blood
Prostatic Neoplasms / blood
Serum Albumin
Stomach Neoplasms / blood
Time Factors
Urinary Bladder Neoplasms / blood
Reg. No./Substance:
0/Blood Proteins; 0/Serum Albumin; 57-88-5/Cholesterol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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