| The possible involvement of nasal allergy in allergic keratoconjunctivitis. | |
| | |
MedLine Citation:
|
PMID: 19011606 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
|
PURPOSE: Allergic keratoconjunctivitis coexists regularly with allergic rhinitis. However, little is known about the relationship between these conditions. The purpose of this study was to investigate the possible involvement of nasal allergy in keratoconjunctivitis by means of nasal challenge with allergen (NPT), in combination with recording of the ocular symptoms. METHODS: In 26 patients suffering from atopic (n=15) or vernal (n=11) keratoconjunctivitis showing positive history and skin tests, but responding insufficiently to the local ophthalmologic therapy, 71 NPTs with inhalant allergens were performed and combined with the recording of the ocular response. In 11 control subjects with allergic rhinitis, but without ocular disease history, 11 positive NPTs were repeated and supplemented with the registration of the ocular features. RESULTS: Of the 26 patients, 24 developed 51 positive nasal responses (NRs; P<0.01), 43 of which were accompanied by significant ocular response (P<0.01). No ocular responses were measured during the 26 PBS control challenges (P>0.05) or during 11 repeated NPTs in control subjects (P>0.2). CONCLUSIONS: These results give evidence for possible involvement of nasal allergy in some cases of keratoconjunctivitis. They also show diagnostic value of nasal challenges with allergen in combination with registration of the ocular symptoms in such patients, allowing then consideration of additional therapeutic measures concerning the nasal allergy. |
| | |
Authors:
|
Z Pelikan |
Related Documents
:
|
1536756 - Resolution of oral lichenoid lesions after replacement of amalgam restorations in patie... 2336526 - Diagnostic value of acoustic rhinometry: patients with allergic and vasomotor rhinitis ... 2262716 - Thalidomide in type-2 lepra reaction--a clinical experience. 9152806 - Flow cytometry tear analysis in patients with chronic allergic conjunctivitis. 3136636 - Efficacy and safety of class ic antiarrhythmic agents for the treatment of coexisting s... 18705896 - Stroke and atherothrombosis: an update on the role of antiplatelet therapy. |
Publication Detail:
|
Type: Journal Article Date: 2008-11-14 |
Journal Detail:
|
Title: Eye (London, England) Volume: 23 ISSN: 1476-5454 ISO Abbreviation: Eye (Lond) Publication Date: 2009 Aug |
Date Detail:
|
Created Date: 2009-08-13 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8703986 Medline TA: Eye (Lond) Country: England |
Other Details:
|
Languages: eng Pagination: 1653-60 Citation Subset: IM |
Affiliation:
|
Allergy Research Foundation, Breda, The Netherlands. zpelikan@casema.nl |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: An assessment of readiness for behaviour change in patients prescribed ocular hypotensive therapy.
Next Document: The groningen longitudinal glaucoma study III. The predictive value of frequency-doubling perimetry ...