| A possible effect of amisulpride on a prolactinoma growth in a woman with borderline personality disorder. | |
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MedLine Citation:
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PMID: 15225684 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The authors report the case of a woman with borderline personality disorder who developed a prolactinoma probably induced by amisulpride. This patient was treated with 300 mg of amisulpride per day for a delirium. Her brain MRI was normal. Four months later this patient developed a micro-adenoma (5mm) on the right side of the pituitary gland with amenorrhea and galactorrhea. Amisulpride treatment was withdrawn and replaced by a treatment of quetiapine 100 mg day(-1). The hyperprolactinemia symptoms disappeared. This report shows that the short-term use of amisulpride treatment was linked to an elevation in the PRL level with a possible induction of a pituitary adenoma. |
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Authors:
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Nader Perroud; Philippe Huguelet |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Pharmacological research : the official journal of the Italian Pharmacological Society Volume: 50 ISSN: 1043-6618 ISO Abbreviation: Pharmacol. Res. Publication Date: 2004 Sep |
Date Detail:
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Created Date: 2004-06-30 Completed Date: 2005-02-08 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8907422 Medline TA: Pharmacol Res Country: England |
Other Details:
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Languages: eng Pagination: 377-9 Citation Subset: IM |
Affiliation:
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Département de Psychiatrie, Hôpitaux Universitaires de Genève, 36, Rue du XXXI Décembre, 1207 Geneva, Switzerland. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Borderline Personality Disorder / blood, drug therapy* Female Humans Pituitary Neoplasms / blood, chemically induced* Prolactin / blood Prolactinoma / blood, chemically induced* Sulpiride / adverse effects*, analogs & derivatives* |
| Chemical | |
Reg. No./Substance:
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15676-16-1/Sulpiride; 53583-79-2/sultopride; 9002-62-4/Prolactin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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