Document Detail


A population-based study of the outcome after small bowel atresia/stenosis in New South Wales and the Australian Capital Territory, Australia, 1992-2003.
MedLine Citation:
PMID:  18358286     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: The purpose of the study was to describe the incidence, epidemiology, and survival of infants with small bowel atresia/stenosis in New South Wales (NSW) and the Australian Capital Territory (ACT), Australia. METHODS: A population-based cohort study was conducted of infants diagnosed with small bowel atresia/stenosis in NSW and the ACT from 1992 to 2003. Data were obtained from the prospectively collated NSW and ACT Neonatal Intensive Care Units' data collection. Individual risk factors for mortality were assessed using the chi(2) test. RESULTS: The incidence of small bowel atresia/stenosis in NSW and the ACT was 2.9 per 10,000 births. Of 299 infants identified with small bowel atresia, 13 were stillborn. Of the 286 live born infants, most (52%) were delivered preterm (<37 weeks' gestation) with an 87% survival, whereas 48% were term with a 98% survival. More than half the infants (54%) had an associated birth defect. The overall mortality was 8%. Prematurity and low birth weight were identified as independent risk factors for mortality (P < .001). CONCLUSIONS: This study of small bowel atresia/stenosis provides population-based outcomes for clinicians and families. It is important to investigate infants with small bowel atresia for associated birth defects. Although the mortality rate has decreased over the last 50 years, it remains substantial at 8% and is higher in premature and low birth weight infants.
Authors:
Karen Walker; Nadia Badawi; Celine H Hamid; Amish Vora; Robert Halliday; Claire Taylor; Edward Shi; G T Roy; Edward Simpson; Andrew J A Holland;
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of pediatric surgery     Volume:  43     ISSN:  1531-5037     ISO Abbreviation:  J. Pediatr. Surg.     Publication Date:  2008 Mar 
Date Detail:
Created Date:  2008-03-24     Completed Date:  2008-05-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0052631     Medline TA:  J Pediatr Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  484-8     Citation Subset:  IM    
Affiliation:
Department of Paediatrics and Child Health, Grace Centre for Newborn Care, The Children's Hospital at Westmead, The University of Sydney, Westmead, NSW 2145, Australia. karenw4@chw.edu.au
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MeSH Terms
Descriptor/Qualifier:
Australian Capital Territory / epidemiology
Cause of Death
Cohort Studies
Congenital Abnormalities / diagnosis,  epidemiology*,  surgery
Digestive System Surgical Procedures / methods,  mortality*
Female
Humans
Incidence
Infant
Infant, Newborn
Infant, Premature
Infant, Very Low Birth Weight
Intensive Care Units, Neonatal
Intestinal Atresia / diagnosis,  epidemiology*,  surgery
Intestinal Obstruction / congenital,  epidemiology*,  surgery
Intestine, Small / abnormalities*
Male
New South Wales / epidemiology
Postoperative Complications / diagnosis,  mortality
Probability
Registries
Risk Assessment
Survival Analysis
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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