Document Detail

A population-based study of extra-cardiac anomalies in children with congenital cardiac malformations.
MedLine Citation:
PMID:  15679995     Owner:  NLM     Status:  MEDLINE    
We describe the prevalence of extra-cardiac anomalies in children with congenital cardiac malformations, and their impact on survival, compared to the outcome in children with the congenital cardiac lesions as the only recognised anomaly. Our population comprises the 3527 children born with congenital cardiac anomalies between 1990 and 1999, and registered at the largest tertiary centre for Paediatric Cardiology in Norway. Extra-cardiac anomalies were found in one-fifth of the population, with Down's syndrome accounting for nearly one-third. Survival improved for children born between 1995 and 1999 compared with those born in the period from 1990 to 1994 for all groups, except for children with additional extra-cardiac anomalies in the absence of Down's syndrome. The results were the same for children undergoing surgical treatment of their cardiac malformation. The survival in children with Down's syndrome improved in comparable fashion to those without extra-cardiac anomalies. Children with extra-cardiac anomalies in the absence of Down's syndrome represent a heterogeneous group, with varying patterns of survival. Survival did not improve in these latter patients during the period of our study.
Leif Eskedal; Petter Hagemo; Anne Eskild; Geir Aamodt; Karry Stephen Seiler; Erik Thaulow
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Cardiology in the young     Volume:  14     ISSN:  1047-9511     ISO Abbreviation:  Cardiol Young     Publication Date:  2004 Dec 
Date Detail:
Created Date:  2005-01-31     Completed Date:  2005-06-09     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9200019     Medline TA:  Cardiol Young     Country:  England    
Other Details:
Languages:  eng     Pagination:  600-7     Citation Subset:  IM    
Department of Pediatrics, Soerlandet Regional Hospital, Kristiansand, Norway.
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MeSH Terms
Abnormalities, Multiple / epidemiology*,  mortality
Down Syndrome / epidemiology,  mortality
Heart Defects, Congenital / epidemiology*,  mortality
Infant, Newborn
Norway / epidemiology

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