| A population-based analysis of the effect of autologous hematopoietic cell transplantation in the treatment of multiple myeloma. | |
| | |
MedLine Citation:
|
PMID: 23286335 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
ABSTRACT This population registry-based study followed all cases of myeloma diagnosed in New South Wales Australia during 2002 to 2005 and compared survival outcomes of those who proceeded to autologous hematopoietic cell transplant (HCT) with those who did not. Data available consisted of demographic details and survival, and did not include disease details or treatment type or response. Of 708 patients, 270 (38%) had HCT. The 5-year overall survival (OS) of HCT recipients was significantly better than those who did not proceed to HCT (62% vs 54%, P=0.003). HCT was a significant favourable risk factor for OS, while age over 60 was an adverse risk factor. However, for patients alive at 1 year from diagnosis, there was no significant difference in survival between HCT and non-HCT patients, suggesting that worse disease biology and/or co-existing morbidities were likely to be major reasons for the poorer outcome for non HCT patients. |
| | |
Authors:
|
Ian Nivison-Smith; Judy M Simpson; Anthony J Dodds; David Df Ma; Jeff Szer; Kenneth F Bradstock |
Related Documents
:
|
23142075 - The prognostic value of vascular endothelial growth factor in ovarian cancer: a systema... 23093845 - Overexpression of runt-related transcription factor-2 is associated with advanced tumor... 23534765 - Prognostic impact of cyclin d1, cyclin e and p53 on gastroenteropancreatic neuroendocri... 2064265 - Nasopharyngeal carcinoma: modes of presentation. 19374545 - Malignant pleural mesothelioma. 21063195 - Increased recurrences using intensity-modulated radiation therapy in the postoperative ... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2013-1-4 |
Journal Detail:
|
Title: Leukemia & lymphoma Volume: - ISSN: 1029-2403 ISO Abbreviation: Leuk. Lymphoma Publication Date: 2013 Jan |
Date Detail:
|
Created Date: 2013-1-4 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9007422 Medline TA: Leuk Lymphoma Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: MicroRNAs expression in chronic lymphocytic leukemia developing autoimmune hemolytic anemia.
Next Document: Effects of within-colony competition on body size asymmetries and reproductive skew in a social spid...