Document Detail


A polyurethane cuffed endotracheal tube is associated with decreased rates of ventilator-associated pneumonia.
MedLine Citation:
PMID:  20655698     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: The aim of this study was to determine whether the use of a polyurethane-cuffed endotracheal tube would result in a decrease in ventilator-associated pneumonia rate.
MATERIALS AND METHODS: We replaced conventional endotracheal tube with a polyurethane-cuff endotracheal tube (Microcuff, Kimberly-Clark Corporation, Rosewell, Ga) in all adult mechanically ventilated patients throughout our large academic hospital from July 2007 to June 2008. We retrospectively compared the rates of ventilator-associated pneumonia before, during, and after the intervention year by interrupted time-series analysis.
RESULTS: Ventilator-associated pneumonia rates decreased from 5.3 per 1000 ventilator days before the use of the polyurethane-cuffed endotracheal tube to 2.8 per 1000 ventilator days during the intervention year (P = .0138). During the first 3 months after return to conventional tubes, the rate of ventilator-associated pneumonia was 3.5/1000 ventilator days. Use of the polyurethane-cuffed endotracheal tube was associated with an incidence risk ratio of ventilator-associated pneumonia of 0.572 (95% confidence interval, 0.340-0.963). In statistical regression analysis controlling for other possible alterations in the hospital environment, as measured by rate of tracheostomy-ventilator-associated pneumonia, the incidence risk ratio of ventilator-associated pneumonia in patients intubated with polyurethane-cuffed endotracheal tube was 0.565 (P = .032; 95% confidence interval, 0.335-0.953).
CONCLUSIONS: Use of a polyurethane-cuffed endotracheal tube was associated with a significant decrease in the rate of ventilator-associated pneumonia in our study.
Authors:
Melissa A Miller; Jennifer L Arndt; Mark A Konkle; Carol E Chenoweth; Theodore J Iwashyna; Kevin R Flaherty; Robert C Hyzy
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Publication Detail:
Type:  Journal Article     Date:  2010-07-23
Journal Detail:
Title:  Journal of critical care     Volume:  26     ISSN:  1557-8615     ISO Abbreviation:  J Crit Care     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-05-27     Completed Date:  2011-10-24     Revised Date:  2014-05-21    
Medline Journal Info:
Nlm Unique ID:  8610642     Medline TA:  J Crit Care     Country:  United States    
Other Details:
Languages:  eng     Pagination:  280-6     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier Inc. All rights reserved.
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MeSH Terms
Descriptor/Qualifier:
Adult
Equipment Design
Humans
Incidence
Intubation, Intratracheal / instrumentation*
Pneumonia, Ventilator-Associated / epidemiology,  prevention & control*
Polyurethanes*
Respiration, Artificial / adverse effects,  methods*
Retrospective Studies
Grant Support
ID/Acronym/Agency:
T32 HL007749/HL/NHLBI NIH HHS
Chemical
Reg. No./Substance:
0/Polyurethanes
Comments/Corrections

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