Document Detail


An HIV1/2 point of care test on sputum for screening TB/HIV co-infection in central India - Will it work?
MedLine Citation:
PMID:  23375036     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
OBJECTIVE: To determine whether the OraQuick® HIV-1/2 Assay (OraSure Technologies, Inc., Bethlehem, PA, USA) in sputum is a valid tool for HIV surveillance among TB patients.
METHODS: A cross sectional study was carried out on sputa of patients diagnosed with tuberculosis. Sputa were tested for antibodies to HIV using OraQuick® HIV-1/2 Assay (OraSure Technologies, Inc., Bethlehem, PA, USA). The results were compared with results of serum ELISA.
RESULTS: Compared to serum ELISA, the OraQuick® HIV-1/2 Assay in sputum specimens reported 90% sensitivity (9/10) and 100% specificity (307/307), with a positive predictive value of 100% (95%CI: 66.37%-100.00%) and a negative predictive value of 99.68% (95%CI: 98.20%-99.99%).
CONCLUSIONS: This testing method may provide a useful strategy for conducting HIV surveillance in possible co-infected TB patients at peripheral centres. Since there is no investment on infrastructure, it may be possible for paramedical health professionals to carry out the test, particularly in areas with low HIV endemicity.
Authors:
Prabha Desikan; Sajal De; Nitika Pant Pai; Pradyumna K Mishra; Kaushal Kumar; Nikita Panwalkar; Mayanka Verma; Zia Ul Hasan; Kewal K Maudar
Related Documents :
25040336 - Outcomes of intravenous tissue plasminogen activator for acute ischaemic stroke in hiv-...
24738846 - Barriers to hepatitis c antiviral therapy in hiv/hcv co-infected patients in the united...
24050726 - Lipid profile and hepatic steatosis in hepatitis c infected egyptian survivors of child...
18670226 - Suicidal ideation in uk hiv clinic attenders.
2155606 - The cytosolic concentration of phosphate determines the maximal rate of glycogenolysis ...
16933366 - Drug abuse, innate immunity and hepatitis c virus.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Asian Pacific journal of tropical medicine     Volume:  6     ISSN:  1995-7645     ISO Abbreviation:  Asian Pac J Trop Med     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-02-04     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101533720     Medline TA:  Asian Pac J Trop Med     Country:  Singapore    
Other Details:
Languages:  eng     Pagination:  216-9     Citation Subset:  IM    
Copyright Information:
Copyright © 2013 Hainan Medical College. Published by Elsevier B.V. All rights reserved.
Affiliation:
Department of Microbiology, Bhopal Memorial Hospital and Research Centre, Bhopal, India. Electronic address: prabhadesikan@yahoo.com.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Crypto-Giardia antigen rapid test versus conventional modified Ziehl-Neelsen acid fast staining meth...
Next Document:  GRK6 expression in patients with hepatocellular carcinoma.