| A pilot study to determine genetic polymorphism in Mycobacterium tuberculosis isolates in Central India. | |
| | |
MedLine Citation:
|
PMID: 23183476 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
This study was carried out to identify predominant spoligotypes responsible for transmission and prevalence of tuberculosis in central India since there is no data available about the genetic biodiversity of Mycobacterium tuberculosis isolates from patients with tuberculosis in this region. 35 strains of Mycobacterium tuberculosis were subjected to spoligotyping according to the standard protocol. A total of 25 strains out of the 35 (71.42%) could be grouped in to 6 clusters. The largest cluster comprised 8 isolates. Unique (Non-clustered) spoligotypes were seen in 10 isolates, Nine strains did not match the data base (Spol DB-4 data base). The results indicate that there may be a number of orphan strains unique to this geographical area. Further studies on a larger sample size derived from this area would help us delineate the epidemiology of Mycobacterium tuberculosis infection in this area. |
| | |
Authors:
|
P Desikan; D S Chauhan; P Sharma; N Panwalkar; S Gautam; V M Katoch |
Related Documents
:
|
23195556 - Interference in quorum sensing signal transmission amongst microbial species. 23444796 - Current problems concerning parasitology and mycology with regard to diseases of the sk... 23199276 - Pesticide susceptibility status of anopheles mosquitoes in four flood-affected district... 23463246 - Echinocandins: production and applications. 10223946 - In vitro susceptibilities of clinical yeast isolates to the new antifungal eberconazole... 12809806 - Genotypically distinct leishmania colombiensis isolates from venezuela cause both cutan... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Indian journal of medical microbiology Volume: 30 ISSN: 1998-3646 ISO Abbreviation: Indian J Med Microbiol Publication Date: 2012 Oct-Dec |
Date Detail:
|
Created Date: 2012-11-27 Completed Date: 2013-04-29 Revised Date: 2013-05-02 |
Medline Journal Info:
|
Nlm Unique ID: 8700903 Medline TA: Indian J Med Microbiol Country: India |
Other Details:
|
Languages: eng Pagination: 470-3 Citation Subset: IM |
Affiliation:
|
Department of Microbiology, Bhopal Memorial Hospital and Research Centre, Raisen Bypass Road, Karond, Bhopal, India. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Cluster Analysis Genotype Humans India Molecular Epidemiology Molecular Typing* Mycobacterium tuberculosis / classification*, genetics*, isolation & purification Polymorphism, Genetic* Tuberculosis / epidemiology*, microbiology* |
| Comments/Corrections | |
Erratum In:
|
Indian J Med Microbiol. 2013 Jan-Mar;31(1):104 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Markers of pathogenicity islands in strains of Aeromonas species of clinical and environmental origi...
Next Document: Recurrent meningitis due to Salmonella enteritidis: A case report from Kashmir India.