| A pilot study identifying type V collagenolytic activity in human amniotic fluid. | |
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MedLine Citation:
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PMID: 9259908 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Amniorrhexis complicates pregnancies if it occurs in a preterm pregnancy or remote from the onset of labor in a term pregnancy. There are different collagen types (I-V) that create the extracellular matrix of the amnion. Collagenases specific to these collagen types, with the exception of type V collagen, are found in human amniotic fluid, fibroblasts, polymorphonuclear leukocytes and bacteria. Type V collagen is a major component of the amniotic basement membrane and is responsible for maintaining a barrier to bacteria and to the loss of amniotic fluid. We sought to find evidence of type V collagenolytic activity in human amniotic fluid obtained from pregnancies in different clinical states. |
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Authors:
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W J Polzin; E G Lockrow; W K Morishige |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: American journal of perinatology Volume: 14 ISSN: 0735-1631 ISO Abbreviation: Am J Perinatol Publication Date: 1997 Feb |
Date Detail:
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Created Date: 1997-09-11 Completed Date: 1997-09-11 Revised Date: 2009-11-19 |
Medline Journal Info:
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Nlm Unique ID: 8405212 Medline TA: Am J Perinatol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 103-6 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, Tripler Army Medical Center, Tripler AMC, Hawaii, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Amniocentesis Amnion / chemistry, enzymology Amniotic Fluid / enzymology* Autoradiography Bacteria / enzymology Basement Membrane / chemistry Collagen / analysis, classification Collagenases / analysis Electrophoresis, Polyacrylamide Gel Extracellular Matrix Proteins / analysis Female Fetal Membranes, Premature Rupture / enzymology Fetal Organ Maturity Fibroblasts / enzymology Genetic Testing Humans Lung / embryology Matrix Metalloproteinase 8 Microbial Collagenase / analysis* Neutrophils / enzymology Obstetric Labor, Premature / enzymology Pilot Projects Placenta / enzymology Pregnancy Sodium Dodecyl Sulfate Surface-Active Agents |
| Chemical | |
Reg. No./Substance:
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0/Extracellular Matrix Proteins; 0/Surface-Active Agents; 151-21-3/Sodium Dodecyl Sulfate; 9007-34-5/Collagen; EC 3.4.24.-/Collagenases; EC 3.4.24.-/type V collagen-degrading enzyme; EC 3.4.24.3/Microbial Collagenase; EC 3.4.24.34/Matrix Metalloproteinase 8 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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