Document Detail

A phytotherapeutic approach to Nigerian anti-HIV and immunomodulatory drug discovery.
MedLine Citation:
PMID:  18050777     Owner:  NLM     Status:  MEDLINE    
Effective therapies for management of HIV infection are top priority due to the high rate of morbidity and mortality of the disease, globally and this has assumed devastating dimension in the African continent. In Nigeria, many patients use herbal remedies for the management of HIV/AIDS, without sufficient scientific proof that they possess anti-HIV activity. In this report, the role of the tropical rainforest plants, identified through ethnomedical approach, as a source of antiviral and immunomodulating agents is highlighted. Some plant derived antiviral and immunomodulatory agents are briefly discussed. An outline of in vitro antiviral and immunomodulatory assays that can be adapted to the Nigerian environment is given. The urgent need to identify and evaluate the medicinal plants in the Nigerian biodiversity reputedly used for management of viral infections is also emphasized.
E O Ajaiyeoba; O O Ogbole
Related Documents :
7811547 - Glutathione precursor and antioxidant activities of n-acetylcysteine and oxothiazolidin...
21776297 - Major hiv resistance mutations in untreated romanian patients.
18585917 - Phenyl phosphotriester derivatives of azt: variations upon the sate moiety.
16140017 - Two new sesquiterpenoids and anti-hiv principles from the root bark of zanthoxylum aila...
15793867 - Four-year follow up of hepatitis c patients vaccinated against hepatitis b virus.
1733637 - Hyper-response of serum igg1 to staphylococcus aureus peptidoglycan in patients with hy...
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  African journal of medicine and medical sciences     Volume:  35 Suppl     ISSN:  0309-3913     ISO Abbreviation:  Afr J Med Med Sci     Publication Date:  2006 Dec 
Date Detail:
Created Date:  2007-12-03     Completed Date:  2008-02-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7801013     Medline TA:  Afr J Med Med Sci     Country:  Nigeria    
Other Details:
Languages:  eng     Pagination:  71-6     Citation Subset:  IM    
Department of Pharmnacognosy, Faculty of Pharmacy, University of Ibadan, Ibadan, Nigeria.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
HIV Infections / drug therapy*,  epidemiology,  immunology
Immunologic Factors / therapeutic use*
Nigeria / epidemiology
Phytotherapy / methods*
Plant Preparations / therapeutic use*
Treatment Outcome
Reg. No./Substance:
0/Immunologic Factors; 0/Plant Preparations

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  AIDS-associated malignancies.
Next Document:  HIV/AIDS and the surgeon.