Document Detail

The physiological significance of coronary aneurysms in Kawasaki disease.
MedLine Citation:
PMID:  22157479     Owner:  NLM     Status:  In-Data-Review    
Aims: A coronary aneurysm is one of the most frequent complications of Kawasaki disease, and yet there is little information concerning the haemodynamic abnormality influenced by the existence of a coronary aneurysm. When blood flow passes through an aneurysm, the turbulence that then occurs means that part of the initial energy is lost, and that energy loss could cause a drop in pressure, such as when passing through a stenotic lesion. The aim of this study is to prove the hypothesis that a giant aneurysm haemodynamically acts in a manner similar to that of stenosis. Methods and results: The study population consisted of 47 patients with a simple coronary aneurysm after Kawasaki disease. Fractional flow reserve was measured in 32 coronary aneurysms. The fractional flow reserve in non-giant aneurysms was 0.95±0.03 and 0.90±0.03 in giant aneurysms (p=0.0004). Conclusions: The present data demonstrated that the coronary aneurysm could give rise to a small decline of pressure along the artery. Since no aneurysm demonstrated a fractional flow reserve under 0.75, a simple aneurysm would not cause coronary ischaemia by itself. However, it could trigger a coronary ischaemia in case of multiple coronary aneurysms and a coronary aneurysm with mild stenosis.
Tomoaki Murakami; Nobuhiro Tanaka
Related Documents :
2679779 - Effect of cold pressor test on the internal diameter of the radial artery.
2337229 - Does the radial arterial line degrade the performance of a pulse oximeter?
1561269 - A free arterialized venous loop flap.
22244859 - Early experience with the snorkel technique for juxtarenal aneurysms.
21990529 - Newtonian viscosity model could overestimate wall shear stress in intracranial aneurysm...
14504819 - The retrograde neurocutaneous island flap of the dorsal branch of the ulnar nerve: anat...
12928849 - Mycotic abdominal aortic pseudoaneurysm caused by a penetrating atherosclerotic ulcer: ...
20609819 - A simple technique to reduce tension on coronary button anastomosis in aortic root surg...
17342369 - Prothrombin 20210 g/a defect as a cause of mesenteric venous infarction: report of a case.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology     Volume:  7     ISSN:  1969-6213     ISO Abbreviation:  EuroIntervention     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-12-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101251040     Medline TA:  EuroIntervention     Country:  France    
Other Details:
Languages:  eng     Pagination:  944-7     Citation Subset:  IM    
Department of Pediatrics, Chiba Cardiovascular, Ichihara Center, Chiba, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Comparison of novel 6.5 Fr sheathless guiding catheters versus 5 Fr guiding catheters for transradia...
Next Document:  Paclitaxel-eluting stents reduce neointimal hyperplasia compared to bare metal stents in saphenous v...