| The physiological effects of short-term smoking cessation in claudicants. | |
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MedLine Citation:
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PMID: 19017673 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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INTRODUCTION: Smoking contributes to atherosclerosis and causes significant postoperative morbidity. New antismoking law forces short-term pre-operative abstinence. Demonstrable clinical benefit might motivate complete cessation. Our aim was to determine the effects of 24-hr smoking cessation on cardiorespiratory function and claudication distance. METHODS: Smoking claudicants were randomized to 24hr smoking or abstinence. Following these separate periods, cardiopulmonary exercise testing was performed. Pre- and post-exercise, serum lactate and ankle brachial pressure index (ABPI) were measured. During exercise, cardiorespiratory function, initial and absolute claudication (IC,AC) distances and visual analogue scores (VAS) of pain were recorded. RESULTS: 16 patients completed both tests. IC, AC and VAS were unchanged with abstinence (P = .43, .66, .96, .83). ABPI drop post-exercise was unchanged with abstinence (P = .08, .09). Cardiorespiratory function was not affected by smoking cessation. CONCLUSION: Cardiorespiratory function and claudication symptoms are unchanged following 24-hr smoking cessation. No deterioration in respiratory function is important when considering anaesthetic administration. However, lack of symptomatic improvement may discourage patients from abstaining. Further investigation should determine correlation between short-term abstinence and postoperative morbidity. |
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Authors:
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K J Dickinson; A J Cockbain; W MacDonald; M Shah; S Homer-Vanniasinkam |
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Publication Detail:
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Type: Comparative Study; Journal Article Date: 2008-11-17 |
Journal Detail:
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Title: Angiology Volume: 60 ISSN: 1940-1574 ISO Abbreviation: Angiology Publication Date: 2009 Apr-May |
Date Detail:
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Created Date: 2009-04-20 Completed Date: 2009-05-07 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0203706 Medline TA: Angiology Country: United States |
Other Details:
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Languages: eng Pagination: 159-63 Citation Subset: IM |
Affiliation:
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Leeds Vascular Institute, Leeds General Infirmary, Leeds, United Kingdom. kdickinson0@hotmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Exercise Test Female Follow-Up Studies Hemodynamics / physiology* Humans Intermittent Claudication / physiopathology*, therapy Male Middle Aged Respiratory Function Tests Respiratory Physiological Phenomena Smoking / adverse effects Smoking Cessation / methods* Time Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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