Document Detail


The physics behind the larger scale organization of DNA in eukaryotes.
MedLine Citation:
PMID:  19571359     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In this paper, we discuss in detail the organization of chromatin during a cell cycle at several levels. We show that current experimental data on large-scale chromatin organization have not yet reached the level of precision to allow for detailed modeling. We speculate in some detail about the possible physics underlying the larger scale chromatin organization.
Authors:
Marc Emanuel; Nima Hamedani Radja; Andreas Henriksson; Helmut Schiessel
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-07-01
Journal Detail:
Title:  Physical biology     Volume:  6     ISSN:  1478-3975     ISO Abbreviation:  Phys Biol     Publication Date:  2009  
Date Detail:
Created Date:  2009-07-02     Completed Date:  2009-09-21     Revised Date:  2010-03-11    
Medline Journal Info:
Nlm Unique ID:  101197454     Medline TA:  Phys Biol     Country:  England    
Other Details:
Languages:  eng     Pagination:  025008     Citation Subset:  IM    
Affiliation:
Instituut Lorentz voor de theoretische natuurkunde, Universiteit Leiden, PO Box 9506, NL-2300 RA Leiden, The Netherlands. emanuel@lorentz.leidenuniv.nl
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MeSH Terms
Descriptor/Qualifier:
Animals
Binding Sites
Cell Cycle
Chromatin*
DNA / chemistry*
Elasticity
Eukaryotic Cells / chemistry*
Models, Molecular
Nucleic Acid Conformation
Static Electricity
Chemical
Reg. No./Substance:
0/Chromatin; 9007-49-2/DNA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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