| The pharmacology of pain signalling. | |
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MedLine Citation:
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PMID: 8219729 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Recent advances in pain research illustrate the analytical power of modern neurosciences in a field previously accessible only to methods of systems biology. Novel molecular and cellular biological techniques have changed the face of pain research by detailing the multiplicity of pain transducing and pain suppressive systems which involve neuronal and hormonal systems acting in concert to help the individual to cope with pain. The introduction of concepts of neuronal plasticity in this field has led to important therapeutical consequences. Novel compounds and new regimens for drug treatment to prevent activity-dependent long-term changes or to facilitate extinction in pain-related systems are emerging. |
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Authors:
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W Zieglgänsberger; T R Tölle |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Current opinion in neurobiology Volume: 3 ISSN: 0959-4388 ISO Abbreviation: Curr. Opin. Neurobiol. Publication Date: 1993 Aug |
Date Detail:
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Created Date: 1993-12-13 Completed Date: 1993-12-13 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 9111376 Medline TA: Curr Opin Neurobiol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 611-8 Citation Subset: IM |
Affiliation:
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Max-Planck-Institute of Psychiatry, Clinical Institute, München, Germany. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Analgesics
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pharmacology Animals Endorphins / physiology Humans Models, Biological Neurons / drug effects, physiology* Neuropeptides / physiology Nociceptors / physiology Pain / physiopathology* Receptors, Glutamate / physiology Receptors, N-Methyl-D-Aspartate / physiology Signal Transduction* Spinal Cord / physiology*, physiopathology |
| Chemical | |
Reg. No./Substance:
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0/Analgesics; 0/Endorphins; 0/Neuropeptides; 0/Receptors, Glutamate; 0/Receptors, N-Methyl-D-Aspartate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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