Document Detail

A phantom assessment of portable imaging and radio-guided surgery systems with technetium-99m and fluorine-18.
MedLine Citation:
PMID:  22466010     Owner:  NLM     Status:  In-Data-Review    
AIM: To perform a detailed analysis of the performance of mobile intraoperative imaging systems and gamma probes in a phantom set-up, and compare this with a conventional gamma camera.
METHODS: Two separate experiments were performed. In the first, a modified Jaszczak phantom equipped with five Tc-filled hot spheres (0.5-20 ml) was analyzed using Sentinella, declipseSPECT and a conventional gamma camera under three conditions: no background, spheres on the surface of the background activity, and totally immersed spheres (contrast level in both 1: 8). In the second experiment, two phantom spheres (0.5 and 2 ml) filled with Tc and F (infinite contrast, 1: 4 and 1: 8) were measured using the hand-held probes Navigator and GammaLocator DXI. Data analysis consisted of signal-to-background ratios and determination of the full-width at half-maximum (FWHM). A visual scoring was performed by three nuclear medicine physicians.
RESULTS: At infinite contrast, Tc-filled spheres with volumes of at least 2 ml could be detected adequately with all systems (e.g. 2 ml sphere, FWHM: ECAM 11 mm, declipseSPECT 9 mm, Navigator 13 mm, GammaLocator 12 mm). Under decreased contrast conditions, the results for all systems were impaired and the 0.5 ml phantom sphere filled with either Tc or F was only detected accurately by the GammaLocator (FWHM range: 13-17 mm).
CONCLUSION: All systems are suitable for intraoperative sentinel node detection with nearly infinite signal-to-background contrast. At a lower contrast, the GammaLocator performed best for the detection of small volumes at low-contrast ratios regardless of the radionuclide.
Thomas Krohn; Frederik A Verburg; Holger Brockmann; Oliver H Winz; Felix M Mottaghy; Florian F Behrendt
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Nuclear medicine communications     Volume:  33     ISSN:  1473-5628     ISO Abbreviation:  Nucl Med Commun     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-04-02     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8201017     Medline TA:  Nucl Med Commun     Country:  England    
Other Details:
Languages:  eng     Pagination:  452-8     Citation Subset:  IM    
Department of Nuclear Medicine, University Hospital Aachen, RWTH Aachen University, Aachen, Germany.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Design for risk control: the role of usability engineering in the management of use-related risks.
Next Document:  Incremental prognostic value of 99mTc-tetrofosmin early poststress pulmonary uptake. Determination o...