| A phantom assessment of portable imaging and radio-guided surgery systems with technetium-99m and fluorine-18. | |
MedLine Citation:
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PMID: 22466010 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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AIM: To perform a detailed analysis of the performance of mobile intraoperative imaging systems and gamma probes in a phantom set-up, and compare this with a conventional gamma camera. METHODS: Two separate experiments were performed. In the first, a modified Jaszczak phantom equipped with five Tc-filled hot spheres (0.5-20 ml) was analyzed using Sentinella, declipseSPECT and a conventional gamma camera under three conditions: no background, spheres on the surface of the background activity, and totally immersed spheres (contrast level in both 1: 8). In the second experiment, two phantom spheres (0.5 and 2 ml) filled with Tc and F (infinite contrast, 1: 4 and 1: 8) were measured using the hand-held probes Navigator and GammaLocator DXI. Data analysis consisted of signal-to-background ratios and determination of the full-width at half-maximum (FWHM). A visual scoring was performed by three nuclear medicine physicians. RESULTS: At infinite contrast, Tc-filled spheres with volumes of at least 2 ml could be detected adequately with all systems (e.g. 2 ml sphere, FWHM: ECAM 11 mm, declipseSPECT 9 mm, Navigator 13 mm, GammaLocator 12 mm). Under decreased contrast conditions, the results for all systems were impaired and the 0.5 ml phantom sphere filled with either Tc or F was only detected accurately by the GammaLocator (FWHM range: 13-17 mm). CONCLUSION: All systems are suitable for intraoperative sentinel node detection with nearly infinite signal-to-background contrast. At a lower contrast, the GammaLocator performed best for the detection of small volumes at low-contrast ratios regardless of the radionuclide. |
Authors:
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Thomas Krohn; Frederik A Verburg; Holger Brockmann; Oliver H Winz; Felix M Mottaghy; Florian F Behrendt |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Nuclear medicine communications Volume: 33 ISSN: 1473-5628 ISO Abbreviation: Nucl Med Commun Publication Date: 2012 May |
Date Detail:
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Created Date: 2012-04-02 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8201017 Medline TA: Nucl Med Commun Country: England |
Other Details:
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Languages: eng Pagination: 452-8 Citation Subset: IM |
Affiliation:
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Department of Nuclear Medicine, University Hospital Aachen, RWTH Aachen University, Aachen, Germany. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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