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The personality trait self-directedness predicts the amygdala's reaction to appetizing cues in fMRI.
MedLine Citation:
PMID:  22381514     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Personality and neural response to food cues in various mesolimbic brain structures have been linked to eating disorders. We investigated the question of whether personality traits in healthy individuals correlate with the brain activation induced on confrontation with appetizing visual stimuli. Personality was assessed in 27 normal-weight participants (14 women, mean age = 26.0, SD = 3.3 years) with the Temperament and Character Inventory (TCI). After an overnight fast, participants viewed blocks of pictures, half containing appetizing food and the other half showing scrambled pictures as control. After each block, participants rated their appetite. Brain activation was measured using a 3 Tesla MR scanner. Food compared to control stimuli elicited a significantly higher appetite rating, as well as strong activation in the ventral and dorsal visual stream, the fusiform gyrus and consecutive limbic centres such as the parahippocampal gyrus, the amygdala, the thalamus, the insula, the ventral striatum and the orbitofrontal cortex. In a region-of-interest analysis, the TCI trait self-directedness was negatively correlated with mean blood oxygenation level dependent (BOLD) signal change in the right amygdala (r = - .43, p = .025). Ultimately, amygdala reactivity might provide a risk factor for the development of eating disorders.
Authors:
O Grimm; M J Jacob; N B Kroemer; L Krebs; S Vollstädt-Klein; A Kobiella; U Wolfensteller; M N Smolka
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-2-27
Journal Detail:
Title:  Appetite     Volume:  -     ISSN:  1095-8304     ISO Abbreviation:  -     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-3-2     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8006808     Medline TA:  Appetite     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Elsevier Ltd. All rights reserved.
Affiliation:
Department of Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim / University Heidelberg, Mannheim, Germany; Department of Neuropsychology and Clinical Psychology, Central Institute of Mental Health, Medical Faculty Mannheim / University Heidelberg,Mannheim, Germany.
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