| A perinatal pathology view of preterm labor. | |
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MedLine Citation:
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PMID: 11320349 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The development and widespread use of tocolytic agents over the past 2 decades has not appeared to substantially affect the overall incidence of preterm delivery in the United States. Preterm delivery, therefore, remains one of the most poorly controlled and poorly understood mechanisms of perinatal morbidity and mortality and a significant strain on public health resources. The purpose of this review is to examine what is currently understood about the clinical manifestations and indicators of preterm delivery, and what, if any, may be the contribution of placental pathology to the understanding of the structural and functional abnormalities that may precede these clinical signs. Two case studies will be used to show how placental pathology may document a pattern of reproductive failure that eludes current methods of clinical screening. A retrospective analysis of what may have gone wrong in the pregnancies, focusing on the placental lesions, may contribute to a greater understanding of the heterogeneous overall processes behind recurrent idiopathic preterm delivery. Such analysis, in conjunction with known clinical factors, may guide the development of better-directed diagnostics and therapies. |
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Authors:
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K A Starzyk; C M Salafia |
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Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: Medscape women's health Volume: 5 ISSN: 1521-2076 ISO Abbreviation: Medscape Womens Health Publication Date: 2000 Nov |
Date Detail:
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Created Date: 2001-04-26 Completed Date: 2002-01-29 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 100844142 Medline TA: Medscape Womens Health Country: United States |
Other Details:
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Languages: eng Pagination: E1 Citation Subset: K |
Affiliation:
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New England Clinical Communications, Marlborough, Massachusetts, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Female Humans Infant, Newborn Infant, Premature Male Obstetric Labor, Premature / etiology*, pathology Placenta / blood supply, pathology* Pregnancy Pregnancy Complications, Hematologic / pathology* Pregnancy Complications, Infectious / pathology* Risk Factors Streptococcal Infections / pathology Streptococcus agalactiae / isolation & purification Thrombophilia / pathology Umbilical Cord / pathology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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